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The Korean Journal of Pathology 2004;38(5): 350-352.
Extraskeletal Osteosarcoma of the Posterior Mediastinum: A Case Report.
Weon Cheol Han, Hyang Jung Cho, Jai Kyoo Lee, Hyung Bae Moon, Jae Y Ro
1Department of Pathology, Wonkwang University, College of Medicine, Iksan 570-749, Korea.
2Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. sirius0109@hotmail.com
ABSTRACT
Extraskeletal osteosarcoma is a rare malignant tumor of soft tissue. In addition, there are only several cases of osteosarcoma of the mediastinum as a primary site in the world. We report a case of extraskeletal osteosarcoma arising in the posterior mediastinum. A 54-year-old man visited our hospital because of chest pain. Chest CT showed a 12 cm sized huge mediastinal mass. The mass revealed solid and ivory-colored cut surface with multifocally ovoid cystic spaces and hemorrhage. Microscopically, the tumor consisted of polygonal stromal cells, giant cells and varying amounts of neoplastic new bone, and mitotic figures were frequently observed. There were no distant metastasis and regional lymph node involvement.
Key Words: Extraskeletal Osteosarcoma-Mediastinum