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The Korean Journal of Pathology 2003;37(2): 137-140.
Solitary Fibrous Tumor of Meninges in Pituitary Fossa: A Case Report.
Dae Woon Eom, Shin Kwang Khang, Chang Jin Kim, Jae Y Ro
1Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. jaero@www.amc.seoul.kr
2Department of Neurosurgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
ABSTRACT
Solitary fibrous tumor (SFT) was originally described in the pleura. An increased number of extrapulmonary sites of SFTs has been described. We report a case of SFT of the meninges in the pituitary fossa. A 56-year-old man was admitted with a severe headache and visual disturbance. The tumor, with osteolytic bony change, was 3.5 cm in greatest dimension and extended from the sphenoid sinus to the third ventricle level. Histologically, the tumor showed the typical features of a solitary fibrous tumor with no evidence of being high grade. By immunohistochemical study, the tumor cells were positive for CD34, vimentin, and Bcl2, but were negative for epithelial membrane antigen and S-100 protein. When fibrous tumors or tumors with hemangiopericytic vascular pattern involve the meninges, the possibility of their being SFTs should be considered, and a proper immunostaining is recommended. To our knowledge, ours is the first description of a case of SFT occurring at the meninges in the pituitary fossa.