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The Korean Journal of Pathology 2002;36(6): 416-419.
Splenic Lymphangioma: A Report of Three Cases.
Mi Jung Kim, Kyung Ja Cho, Eun Mi Han, Young Joo Lee
1Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. kjc@amc.seoul.kr
2Department of General Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
3Department of Pathology, Cheong Ju Saint Mary's Hospital, Cheongju, Korea.
ABSTRACT
Splenic lymphangioma is a very rare and benign neoplasm. We report three cases of splenic lymphangiomas found in three women aged 71-years-old, 50-years-old, and 46-years-old. All of the three cases consisted of solitary lesions in the spleen and they were not represented as a part of lymphangiomatosis. Splenectomies were done in all cases and enlarged spleens revealed multicystic masses with variable-sized cysts. Histologically, the cysts were lined by flat endothelial cells and filled with acellular pinkish fluid. The cyst walls mainly consisted of hypocellular fibrous tissue with occasional smooth muscle components. The walls were shared by neighboring cysts, or intervened by interspersed splenic parenchymal components. On immunohistochemical stainings, the lining cells were diffusely positive for CD31 and factor VIII-related antigen (FVIII-RAg), while focally positive for CD34 in all cases.
Key Words: Splenic Neoplasms; Lymphangioma
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