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The Korean Journal of Pathology 2002;36(5): 357-361.
Chordoid Glioma: A Report of Two Cases.
Eun Jung Park, Hyun Sik O, Min Cheol Lee
Department of Pathology, Chonnam National University Medical School, Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea. mclee@chonnam.ac.kr
ABSTRACT
Chordoid glioma mainly occurs in the third ventricle, pineal gland, hypothalamus, and suprasella. We report two cases of chordoid gliomas of the third ventricles in adult males. Histologically, the tumors consisted of cords and clusters of oval to polygonal epitheliod cells with abundant cytoplasm. The backgrounds of the tumor show mucinous and lymphoplasmacytic infiltrates. Immunohistochemically, the tumor cells were positive for glial fibrillary acidic protein and negative for epithelial membrane antigen, cytokeratin and neurofilament protein. Histopathologic diagnosis of chordoid glioma should be made judiciously by differentiating them from other chordoid or epithelial tumors of the central nervous system.
Key Words: Brain Neoplasms; Glioma