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The Korean Journal of Pathology 2002;36(2): 132-135.
Meningeal Hemangiopericytoma in a Newborn: A Case Report.
Dong Sug Kim, Seong Ho Kim, Woo Mok Byun, Jeong Ok Hah
1Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea. dskim@med.yu.ac.kr
2Department of Neurosurgery, Yeungnam University College of Medicine, Daegu, Korea.
3Department of Diagnostic Radiology, Yeungnam University College of Medicine, Daegu, Korea.
4Department of Pediatrics, Yeungnam University College of Medicine, Daegu, Korea.
ABSTRACT
Several, but not many, cases of congenital meningeal hemangiopericytoma have been described to date. Herein, a case of meningeal hemangiopericytoma in a newborn is described. The patient was a 2-week-old boy with expanded fontanelles and frequent vomiting. A 5 cm sized mass was found in the left temporo-parietal lobe, which was well circumscribed and lobulated. Histologically the tumor was compatible with anaplastic (malignant) hemangiopericytoma, which showed pleomorphic nuclei, frequent mitotic figures and extensive hemorrhagic necrosis. The tumor cells were immunoreactive for vimentin, but negative for CD34, desmin and S-100 protein. Differential diagnosis for meningeal hemangiopericytoma was discussed, and the fact that meningeal hemangiopericytoma might have occurred congenitally was emphasized.
Key Words: Meningeal Neoplasms-Hemangiopericytoma