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The Korean Journal of Pathology 2001;35(6): 558-560.
Recurrent Malignant Phyllodes Tumor with Liposarcoma.
Ji Shin Lee, Hyung Seok Kim, Jong Jae Jung, Chong Dug Cho
Department of Pathology, Seonam University College of Medicine, Namwon 590-711, Korea. jshinlee@hanmail.net
ABSTRACT
Phyllodes tumors are an uncommon mammary tumors composed of benign epithelial elements and cellular, spindle cell stroma. Adipose differentiation is an uncommon stromal alteration in phyllodes tumors. Herein, a case of recurrent phyllodes tumors with liposarcomatous stroma is described. A 30-year-old female presented with a left breast mass. Histologic examination showed a phyllodes tumor with low-grade malignant potential exhibiting a few mitoses and moderate cellularity. It also contained mature adipose tissue as well as a well-differentiated liposarcomatous area. This tumor recurred 43 months later. The recurrent tumor had a higher cellular density and more mitoses than the primary tumor.
Key Words: Mammary neoplasms; Phyllodes tumor; Liposarcoma