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The Korean Journal of Pathology 2001;35(3): 252-255.
Malignant Gastrointestinal Stromal Tumor of the Esophagus: A Case Report.
Hae Joung Sul, Kyeong Hee Kim, Dae Young Kang
Department of Pathology, College of Medicine, Chungnam National University, Daejeon 301-040, Korea, dykang@cnu.ac.kr
Gastrointestinal stromal tumors (GISTs) predominate in the stomach and small intestine but have rarely been documented in the esophagus. We report a rare case of GIST of the esophagus in a 47-year-old woman. Histologically, the tumors showed a combination of solid, myxoid, and perivascular collar-like patterns, with spindle and epithelioid cells. The tumor cells were positive for CD117, CD34, and S-100 protein and negative for desmin and -smooth muscle actin.
Key Words: Gastrointestinal stromal tumors; C kit proteins; CD34 antigen; Esophageal neoplasms