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The Korean Journal of Pathology 1999;33(9): 745-750.
Symptomatic Graular Cell Tumor Involving Intra- and Suprasellar Area: A case report.
Se Hoon Kim, Sun Ho Kim, Tai Seung Kim
1Department of Pathology, Yonsei University Medical College, Seoul 120-752, Korea.
2Department of Neurosurgery, Yonsei University Medical College, Seoul 120-752, Korea.
Symptomatic parasellar granular cell tumor is a very rare tumor. To the best of our knowledge, 43 cases was be found in the English literatures. We recently experienced a case of a parasellar granular cell tumor in a 61-year-old female who had bilateral temporal hemianopsia and severe panhypopituitarism. The tumor was composed of diffuse sheets of polygonal cells with abundant eosinophilic PAS positive granular cytoplasm. In the immunohistochemical and ultrastructural examinations, the tumor failed to show any evidence of Schwann cell or glial differentiation. These findings suggest that granular cell tumor has heterogenous cell types of origin.
Key Words: Parasellar; Granular cell tumor