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The Korean Journal of Pathology 1999;33(3): 217-220.
Ovarian Mucinous Cystadenocarcinoma with Mural Nodules of Anaplastic Carcinoma: A case report.
Kyu Yun Jang, Woo Sung Moon, Dong Geun Lee
1Department of Pathology, Chonbuk National University Medical School, Chonju 561-180, Korea.
2Institute for Medical Science, Chonju 561-180, Korea.
ABSTRACT
A case of an ovarian mucinous cystadenocarcinoma with mural nodules of anaplastic carcinoma is reported. The patient was a 46-year-old female with a right ovarian cystic mass and underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy. The patient died of the disease in five months. Macroscopically, the right ovarian cyst wall contained numerous well-demarcated mural nodules. Histologically, the cysts were mucinous cystadenocarcinoma, and the nodules were composed of sarcoma-like spindle and polygonal cells with atypia and numerous mitoses. Spindle cells in the mural nodule showed epithelial characteristics by electron microscopy and immunohistochemistry. This case supports an epithelial origin of the mural nodule of anaplastic carcinoma in ovarian mucinous tumors.
Key Words: Mural nodule; Anaplastic carcinoma; Ovary