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The Korean Journal of Pathology 1999;33(2): 121-127.
Cryptosporidium Infection of Human Intestine: An Electron Microscopic Observation.
Min Suk Kim, Yun Kyung Kang, Chul Jong Yoon, Mee Joo, Hye Kyung Lee, Jeong Gi Seo, Je G Chi
1Department of Pathology, Seoul National University College of Medicine, Seoul 110-799, Korea.
2Department of Pediatrics, Seoul National University College of Medicine, Seoul 110-799, Korea.
3Department of Pathology, Inje University Seoul Paik Hospital, Seoul, Korea.
ABSTRACT
Protozoa of the genus Cryptosporidium are small coccidian parasite known to infect the mucosal epithelium of a variety of animals including human, causing fatal course in immunodeficient patients as well as self-limited illness in healthy individuals. Various life cycle stages including trophozoite, meront, merozoite, gametocyte and oocyst in infected mucosa are a diagnostic feature. Electron microscopy (EM) provides sufficient findings for genus and species identification of this parasitic organism. The authors presented scanning and transmission EM findings of Cryptosporidium parvum infection in two children: one with acute lymphoblastic leukemia and the other without any evidence of immune compromise.
Key Words: Cryptosporidium parvum; Human; Intestine; Electron microscopy