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The Korean Journal of Cytopathology 1990;1(2): 147-151.
Fine Needle Aspiration Cytology of Two Cases of Leiomyosarcoma.
Chang Won Ha, Na Hye Myong, Kyung Ja Cho, Ja June Jang
Department of Anatomical Pathology, Korea Cancer Center Hospital, Korea.
Leiomyosarcoma of the soft tissue is a well-defined and characteristic entity histologically, but cytomorphological studes are lacking. A correlative cytological study of 2 cases of leiomyosarcoma is presented. The smears from case 1 were rich in tumor cells and most cells were arranged in large sheets or clusters. The cells showed round to oval nuclei containing fine chromatin and small prominent nucleoli. The smears from case 2 were moderate in cellularity with loose clusters or isolated cells. The characteristic blunt-ended and cigar-shaped nuclei containing coarse chromatin and prominent nucleoli were identified in case 2. Nuclear atypia, prominent nucleoli and high cellularity permit diagnosis of malignancy, although the atypia is generally less pronounced than in the histology. The cytological diagnosis of leiomyosarcoma may be auxiliary in the diagnosis of recurrence or metastasis in the patients with alleged leiomyosarcoma.
Key Words: Leiomyosarcoma; Aspiration cytology