Department of Pathology, Konkuk University School of Medicine, Seoul, Korea
1Department of Pathology, Konkuk University Medical Center, Seoul, Korea
2Department of Obstetrics and Gynecology, Konkuk University School of Medicine, Seoul, Korea
© 2016 The Korean Society of Pathologists/The Korean Society for Cytopathology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Conflicts of Interest
This study was supported by Diatech Korea Co., Ltd. The sponsor had no involvement in the study design, data interpretation, or writing of the manuscript.
Histology |
Cytology |
Total | ||||||
---|---|---|---|---|---|---|---|---|
Negative | ASCUS | ASC-H | LSIL | HSIL | Cancer | Not done | ||
Cervicitis | 42 | 9 | 0 | 7 | 0 | 0 | 7 | 65 |
LSIL | 4 | 8 | 0 | 10 | 1 | 0 | 1 | 24 |
HSIL | 0 | 7 | 1 | 7 | 9 | 0 | 1 | 25 |
Cancer | 1 | 0 | 1 | 0 | 0 | 2 | 0 | 4 |
Total | 47 | 24 | 2 | 24 | 10 | 2 | 9 | 118 |
Total | HC2 |
9G |
PANArray |
|||||||
---|---|---|---|---|---|---|---|---|---|---|
Overall | HR | LR | Other | Overall | HR | LR | Other | |||
Total | 118 | 65 (55.1) | 74 (62.7) | 53 (44.9) | 6 (5.1) | 15 (12.7) | 72 (61.0) | 36 (30.5) | 8 (6.8) | 28 (23.7) |
Single | - | - | 36 | 30 | 6 | - | 39 | 31 | 8 | - |
Multiple | - | - | 23 | 23a | 0 | - | 5 | 5a | 0 | - |
Histology | ||||||||||
Cervicitis | 65 | 18 (27.7) | 27 (41.5) | 13 (20) | 3 (4.6) | 11 (16.9) | 25 (38.5) | 8 (12.3) | 4 (6.2) | 13 (20) |
LSIL | 24 | 19 (79.2) | 20 (83.3) | 14 (58.3) | 3 (12.5) | 3 (12.5) | 21 (87.5) | 10 (41.7) | 4 (16.7) | 7 (29.2) |
HSIL | 25 | 25 (100.0) | 24 (96.0) | 24 (96.0) | 0 | 0 | 24 (96.0) | 18 (72.0) | 0 | 6 (24.0) |
Cancer | 4 | 3 (75.0) | 3 (75.0) | 2 (50.0) | 0 | 1 (25.0) | 2 (50.0) | 0 | 0 | 2 (50.0) |
Cytology | ||||||||||
Negative | 47 | 6 (12.8) | 12 (25.5) | 6 (12.8) | 2 (4.3) | 4 (8.5) | 12 (25.5) | 5 (10.6) | 2 (4.3) | 5 (10.6) |
ASCUS | 24 | 20 (83.3) | 21 (87.5) | 19 (79.2) | 0 | 2 (8.3) | 20 (83.3) | 12 (50.0) | 1 (4.2) | 7 (29.2) |
ASC-H | 2 | 1 (50.0) | 2 (100.0) | 1 (50.0) | 0 | 1 (50.0) | 1 (50.0) | 1 (50.0) | 0 | 0 |
LSIL | 24 | 22 (91.7) | 23 (95.8) | 16 (66.7) | 3 (12.5) | 4 (16.7) | 24 (100.0) | 13 (54.2) | 4 (16.7) | 7 (29.2) |
HSIL | 10 | 10 (100.0) | 9 (90.0) | 8 (80.0) | 1 (10.0) | 0 | 9 (90.0) | 3 (30.0) | 1 (10.0) | 5 (50.0) |
Cancer | 2 | 2 (100.0) | 1 (50.0) | 1 (50.0) | 0 | 0 | 1 (50.0) | 0 | 0 | 1 (50.0) |
Total | 109 | 61 (56.0) | 68 (62.4) | 51 (46.8) | 6 (5.5) | 11 (10.1) | 67 (61.5) | 34 (31.2) | 8 (7.3) | 25 (22.9) |
Values are presented as number (%).
HPV, human papillomavirus; HC2, Hybrid-Capture II assay; 9G, HPV 9G DNA Chip; PANArray, PANArray HPV Genotyping Chip; HR, high-risk HPV; LR, low-risk HPV; Other, other-type HPV; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; ASCUS, atypical squamous cells of undetermined significance; ASC-H, atypical squamous cells-cannot exclude HSIL.
a The combination of HR and LR HPV types was interpreted as HR HPV infection in the classification of multiple infection.
PANArray |
9G |
|||
---|---|---|---|---|
Negative | LR | HR | Other | |
Negative | 39 (88.6) | 0 | 1 (1.9) | 6 (40.0) |
LR | 1 (2.3) | 5 (83.3) | 1 (1.9) | 1 (6.7) |
HR | 1 (2.3) | 1 (16.7) | 33 (62.3) | 1 (6.7) |
Other | 3 (6.8) | 0 | 18 (34.0) | 7 (46.7) |