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The Korean Journal of Pathology 1997;31(12): 1324-1327.
Progression of Dermatofibrosarcoma Proruberans to Malignant Fibrous Histiocytoma: Report of a case.
Hye Rim Park, Eun Ha Jung, Jin Hee Sohn
Department of Pathology, College of Medicine, Hallym University, Seoul 150-020, Korea.
ABSTRACT
A 52-year-old woman was admitted with a palpable mass on the abdominal wall. This tumor had developed at the same site of a previously resected dermatofibrosarcoma protuberans. The biopsy specimen from the recurrent tumor revealed malignant fibrous histiocytoma. Immunohistochemistry with anti-CD34 antibody revealed diffuse linear positivity on the tumor cells of dermatofibrosarcoma protuberans and negativity on malignant fibrous histiocytoma. Anti CD34 antibody was valuable for a differential diagnosis of these two lesions.
Key Words: Dermatofibrosarcoma protuberans; Malignant fibrous histiocytoma; CD34