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The Korean Journal of Pathology 1984;18(3): 293-297.
소아성 당뇨병에 속발한 뇌칸디다증의 부검 1예
An Autopsy Case of Cerebral Candidiasis Associated with Juvenile Diabetes Mellitus
An autopsy case of cerebral abscesses and granulomatous pachymeningitis caused by Candida in a 17-year-old Korean female with juvenile diabetes mellitus is reported and a review of literatures related to the case is presented. At autopsy there was noted markedly diminution of Langerhans' islets, intranuclear vacuolization of the liver cells, diffuse glomerulosclerosis of the kidneys, acute suppurative inflammation of the lungs, granulomata with central necrosis in the meninges, and multiple cerebral abscesses with the granulomatous reaction. The methenamine silver and PAS stains of meningeal and cerebral lesions disclosed many budding yeast cells, pseudohyphae and a few hyphae, consistent with Candida.
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