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HOME > J Pathol Transl Med > Volume 18(2); 1984 > Article
Etc Spindle Cell Carcinoma of the Esophagus -A report of a case-
Journal of Pathology and Translational Medicine 1984;18(2):188-192
DOI: https://doi.org/
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Department of Clinical Pathology, Catholic Medical College, Seoul, Korea

Spindle cell carcinoma is very rare variant of squamous cell carcinoma. This variant had been included in the carcinosarcoma, and also confused with pseudosarcoma. The spindle cell component was proved as squamous cell by electron microscopic examination and tissue culture study. The authors experienced a case of spindle cell cariant of squamous cell carcinoma of the esophagus in a 67 years old male patient. He had been suffered from dysphagia and postprandial chest pain for five month. About ten kilogram of weight was lost during four months prior to this entry. An esophagogram revealed a filling defect of barium on the mid-esophagus, suggesting of a polyp. Laboratory findings, including hemogram, blood chemistry, urinalysis and direct smeaar of sputum for acid-fast bacilli, were all within normal limits. A segmental resection of the esophagus with esophagogastrosomy was performed. On gross examination, there was a polypoid mass, 3.7×2.5×2.0cm, on the esophageal mucosa. It revealed dark brown and dirty surface with firm consistency. On cut section, it showed tan gray to light yellow rough trabeculated cut surface. On the microscopic examination, it was composed of spindle shaped cells with interlacing or whorling pattern. In several areas, bizzare multinucleated tumor giant cells were observed. Varying amount of collagen and reticulin fibers were noted. There were intraepithelial squamous cell carcinoma near the stalk of the polyp, and islands of squamous cells in the spindle cell component. A distinct transitional zone was observed.

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