Abstract

Giant cell carcinoma also called as pleomorptic anaplastic carcinoma is rare and progresses fulminant clinical course. Major diagnostic features are pleomorphic and izarre tumor giant cells with abundant foamy cytoplasm, intense neutrophilic infiltration and leukophagocytosis (emperipolesis) by tumor giant cells. Primary gains cell arcinoma have been reported in lungs, thyroid, pancreas and recently in liver, but this carcinoma in colon has not been described, although giant cell tumor of the bone like neoplasm in colon was reported. It was suggested that this neoplasm was glandular epithelial origin by many authors and confirmed by tissue culture. We have experienced a case of mixed form of primary giant cell carcinoma of colon in a 51 year old male in the Sung-Sim Hospital, Chung-Ang University.