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The Korean Journal of Pathology 1978;12(4): 399-406.
정상 및 질환군에서의 전지질, Cholesterol 및 Lipoprotein 분획치의 비교검토
A Comparative Study on Total Lipid, Cholesterol and Lipoprotein Level in Normal and Various Disease
ABSTRACT
The authors studied serum levels of total lipid, cholesterol and lipoprotein in 118 healthy person, 6 cases of hypertension in 6th decade, 5 cases of cardiovascular accident in 7th decade, 10 cases of diabetes mellitus in 6th decade, 6 cases of stomach cancer in 6th decade, 5 cases of drug intoxication in 3rd decade and 15 cases of liver cirrhosis in 6th decade. Above serum levels in each disease group were compared with those of normal healthy persons in same age group. The results obtained are as followings. 1. In normal control groups, total lipid, cholesterol and each fraction of lipoprotein were determined and presented by age group. 2. Patients with diabetes mellitus revealed significant decrease(p<0.01) only in pre β -fraction of lipoprotein. 3. Patients with drug intoxication disclosed significant decrease(p<0.01) only in pre β -fraction of lipoprotein. 4. Patients with cirrhosis of the liver showed significant decrease both in total lipid and pre β -fraction of lipoprotein(p<0.05, p<0.01). 5. Patients with hypertension, C.V.A. and stomach cancer revealed no significant change(p>0. 05) in total lipid, cholesterol and each fraction of lipoprotein.