Abstract

Authors made an experimental study for hematological changes in acute carbon monoxide poisoning using 54 dogs which were divided into a control group and a CO(2%) inhaled group. The hemoglobin concentration, hematocrit, RBC count, WBC count and differential count were studied at 15, 75 and 135 minutes in each group. The obtained results were as followings: 1. There was an increasing tendency of the hemoglobin concentrations up to 13.7±2.02 gm% from 13.1±2.55 gm% of the control. 2. The values of hematocrit were significantly increased and it was highest at 75 minutes after CO inhalation. 3. RBC counts showed an increasing tendency but it was not so significant. 4. WBC counts were significantly decreased to fifty percent of the control. 5. The neutrophils were also significantly decreased, while the eosinophils were increased at 75 minutes after CO inhalation. The basophils were markedly decreased and lymphocytes were increased significantly. In monocytes there was seen a decreasing tendency. The author thought that the decreases of the WBC counts and neutrophils are against to other reports and it requires further study.