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The Korean Journal of Pathology 1971;5(2): 143-147.
한국인 간장질환의 병리조직학적 검색
국립의료원 병리과
Statistical analysis and histopathological study on hepatic diseases among Koreans
Chung Hee Chi
Department of Pathology National Medical Center, Seoul, Korea
Total 337 cases too liver biopsy specimens and 98 autopsy cases of hepatic diseases obtained at the National Medical Center during the period of 1958 to 1968 were histopathologically examined with statistical analysis for international classification of diseases and correlation between clinical diagnosis and histopathological diagnosis was made. As the result of present study the following conclusions were obtained. 1) By sex, number of male is dominant than female in both biopsy 229 cases (male), 108 cases (Female) 2.1 : 1, and autopsy cases 72(%ale), 26(Female) 2.8 : 1. 2) Among the groups of hepatic lesions cirrhosis is 80.5% (M 4l. 6%, F 38.9%) with highest incidence in biopsy material and average age is 34.5 years. Identical findings are seen in autopsy cases with 57 cases (M 40, F 17) out of 98 cases with the range of 55.6% (M) and 65.4% (F). 3) Post hepatitic cirrhosis is highest among the cirrhotic groups of biopsy material with 88 cases (M 66, F 22) out of total cirrhosis cases of 137(M 95, F 42) and portal 22 cases (15 M, 7 F), post necrotic 15 cases (9 M, 6 F), biliary 7 cases (4 M,3 F) as in decreasing order with exceptional 1 case of nutritional Cirrhosis. 4) Average age of tumor is 44. 1 years and somewhat higher than that of cirrhosis 34. 5 years. Tumors among the biopsy material revealed highest incidence of hepatoma 61 cases, extra bile duct ca. 66 cases, and cholangioma 8 cases in decreasing order. 5) In autopsy material age distribution and frequency of hepatic diseases were mostly similar to that of the biopsy material, however, abscesses were comparatively higher in cadaver material. Post hepatitic cirrhosis was 36 cases out of 137 cases and 16 cases of post necrotic cirrhosis was next to the highest incidence. 6) Analytic pilot study for various histopathologic findings to evaluate the grouping of the hepatic lesions (biopsy) without knowing of previous clinico-pathologic diagnosis or laboratory findings showed no remarkable or significant difference among the disease groups. 7) Correlation between clinical and pathologic diagnosis showed considerable percentage of difference. The difference in abscess and hepatitis was only 9.1%.