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The Korean Journal of Pathology 1997;31(2): 179-181.
Signet Ring Cell Variant of Invasive Lobular Carcinoma of Male Breast.
Seung Sam Paik, Seok Hoon Jeon, Moon Hyang Park, Pa Jong Jung, Jung Dal Lee
1Department of Pathology, College of Medicine, Hanyang University, Seoul 133-792, Korea.
2Department of General Surgery, College of Medicine, Hanyang University, Seoul 133-792, Korea.
ABSTRACT
Lobular carcinoma of the male breast is very rare, because of the absence of lobules in the normal male breast. Herein, a case of lobular carcinoma of the male breast with cellular features of signet ring cells is described. A 57-year-old man presented with a left breast mass. Histologic examination showed classic invasive lobular carcinoma with in situ component. Most infiltrating tumor cells had a prominent signet ring cell appearance. The patient was phenotypically male and had fathered children. There was no history of predisposing factors to breast lesion, such as hormone use or gynecomastia.
Key Words: Lobular carcinoma; Signet ring cell Breast; Male