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The Korean Journal of Pathology 1996;30(11): 1034-1039.
Atypical Polypoid Adenomyomas of the Endometrium: 2 case reports.
Hee Jeong Ahn, Kyu Rae Kim, Yoon Jung Choi, Bok Soo Kim
1Department of Pathology, Kyunghee Pundang CHA General Hospital, Sung-nam, Korea.
2Samsung Medical Center, Seoul, Korea.
Atypical polypoid adenomyoma(APA) is a rare benign polypoid tumor arising in the uterine endometrium which was first designated by Mazur in 1981. Microscopic examination reveals architecturally and cytologically atypical endometrial glands separated by intersecting fascicles of smooth muscle cells. The tumor can be misdiagnosed as endometrial adenocarcinoma with myometrial invasion, especially on microscopic examination of a curettage specimen. However a granulation tissue-like stromal response is absent and the smooth muscle in APA is more cellular than that of normal myometrium. We are reporting 2 cases of APA of the uterine endometrium which are 1.5 cm and 1.7 cm in size, respectively, in a 30 and a 22 year-old women. This is the first report in Korean literature using the immunohistochemical staining for smooth muscle actin and desmin.
Key Words: Atypical polypoid adenomyoma; Uterine endometrium