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The Korean Journal of Pathology 1996;30(10): 933-938.
Alveolar Soft Part Sarcoma of the Uterine Cervix: A case report.
Ghee Young Kwon, Yeon Lim Suh
1Department of Diagnostic Pathology, Samsung Seoul Hospital, Seoul, Korea.
2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea.
ABSTRACT
We report a case of alveolar soft part sarcoma(ASPS) of the uterine cervix in a 57-year-old female. She was presented with vaginal bleeding and underwent total hysterectomy. A 1.1cm-sized, polypoid mass was found at the uterine cervix. Microscopically, it had shown an alveolar arrangement of tumor cells and characteristic Periodic acid-Schiff-positive, diastase-resistant, intracytoplasmic granules. Distinct cytoplasmic crystals were found on the ultrastructural examination and tumor cells showed immunoreactivity for smooth muscle actin, myoglobin and neuron-specific enolase, while nonreactive for desmin, vimentin and S-100 protein. Myogenic origin can be suggested with these immunohistochemical results.
Key Words: Alveolar soft part sarcoma; Uterine cervix; Myogenic origin