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The Korean Journal of Pathology 1996;30(7): 646-648.
Well-Differentiated Papillary Mesothelioma of the Peritoneum: Report of a case.
Ji Eun Kim, So Duk Lim, Kyu Rae Kim, Han Young Choi
1Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
2Department of Diagnostic Pathology, Samsung Seoul Hospital, Seoul, Korea.
3Department of Urology, Samsung Seoul Hospital, Seoul, Korea.
ABSTRACT
We described a case of well differentiated papillary mesothelioma (WDPM) of the peritoneum in a 68-year-old man because of its rarity. It was incidentally found during operation for renal cell carcinoma. Grossly, the tumor appeared as multiple small granules or nodules on the entire peritoneal surface, including serosa of the intestine, omentum and mesentery. Microscopically, characteristic features are papillary, tubulopapillary or solid architecture lined by single layer of uniform, cytologically bland, cuboidal or polygonal mesothelial cells. The tumor cells were positive for EMA, cytokeratin and vimentin, but negative for CEA on immunohistochemical staining. Ultrastructural study showed characteristic long slender microvilli on the surface and intercellular junctions.
Key Words: Mesothelioma; Papillary; Well-differentiated; Peritoneum