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The Korean Journal of Pathology 1996;30(6): 528-532.
Lymphocytic Hypophysitis Presenting with Diabetes Insipidus in a Man: Report of a case.
Woo Sung Moon, Myoung Jae Kang, Dong Geun Lee, Hyung Il Kim, Ho Yeul Choi, Sang Ho Kim
1Department of Pathology, College of Medicine, Chonbuk National University, Chun-ju, Korea.
2Department of Neurosurgery, College of Medicine, Chonbuk National University, Chun-ju, Korea.
ABSTRACT
Lymphocytic hypophysitis is an autoimmune disorder of the pituitary gland which usually occurs in a woman in the postpartum period. Diabetes insipidus is not a major clinical feature of this disorder. We report a case of a 22-year-old man with lymphocytic hypophysitis which presented with diabetes insipidus and also involved his cavernous sinus. This represents the seventh reported and the youngest case of a man with lymphocytic hypophysitis. A comparative study of all six male patients is also presented. We suggest diabetes insipidus should be added to the spectrum of clinical manifestations of this disorder.
Key Words: Lymphocytic hypophysitis; Diabetes insipidus; Man
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