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The Korean Journal of Pathology 1996;30(5): 453-456.
Alpha-Fetoprotein-Producing Carcinoma of the Gallbladder.
Young Ha Oh, Haeng Ji Kang, Hyoung Guen Lee, Eun Kyung Hong, Yong Il Kim, Jung Dal Lee
1Department of Pathology, College of Medicine, Hanyang University, 133-792 Seoul, Korea.
2Department of General Surgery, College of Medicine, Hanyang University, 133-792 Seoul, Korea.
ABSTRACT
Alpha-fetoprotein (AFP) is a well-known tumor marker for hepatocellular carcinoma, hepatoblastoma, and yolk sac tumors. There are several studies on AFP-producing tumors that arose from the gastrointestinal tract, pancreas, lung, kidney, and urachal tract. AFP-producing carcinoma of the gallbladder is extremely rare. We report a case of AFP-producing carcinoma of the gallbladder without liver involvement in a 58-year-old man with a gallstone, on which clinical, morphologic, and immunohistochemical studies were performed.
Key Words: Alpha-fetoprotein-producing carcinoma; Gallbladder