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The Korean Journal of Pathology 1996;30(3): 238-244.
Endometrial Ossification: Clinical and pathological analysis of 7 cases.
Kyu Rae Kim, Dong Hee Choi
1Department of Diagnostic Pathology, Samsung Medical Center, Korea.
2Department of Obstetrics & Gynecology, Cha General hospital, 463-070 Sung-nam, Korea.
Endometrial ossifications in seven patients who presented with secondary or primary infertility were described. Herein, we described step-by-step bone forming process in the endometrium and we compared the clinicopathological features of metaplastic ossification and fetal remnants. In five of seven patients, metaplasia was unquestionable etiology of ossification, which was ocquired in the healing process of postabortion endometritis. Ossifications were recurred during the follow-up periods after total hysteroscopic removal in 2 cases. Three cases were followed by normal pregnancy, after total hysteroscopic removal of bony spicules in 2 cases and with retaining of bony spicules in 1 case. In one other case, bony spicules of fetal remnants were verified by multiple fetal hair shafts and endochondral bone formation. Therefore, the cause of endometrial ossification can only be determined by histological findings and careful past obstetric history.
Key Words: Endometrium; Ossification; Infertility; Metaplasia; Fetal remnants