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The Korean Journal of Pathology 1994;28(1): 96-98.
Sirenomelia: An autopsy case report.
Yeong Ju Woo, Hye Kyoung Yoon, In Sook Lim
Department of Pathology, Pusan Paik Hospital, College of Medicine, Inje University, Pusan, Korea.
Sirenomelia is a severe form of caudal regression syndrome that results in a fusion of the lower extremities, which is not compatible with life. A various spectrum of anomalies affecting primarily the musculoskeletal, genitourinary and gastrointestinal systems also can occur. This rare malformation has a reported incidence rate of approximately 1 in 60,000 births, with a range of 1 to 1 percent of all malformed infants. We experienced a sirenomelic case with combined anomalies of genitourinary, cardiovascular and gastrointestinal systems. Maternal obstetric history revealed oligohydramnios and intrauterine fetal growth retardation, and the baby was spontaneously delivered at 37 weeks of gestational age, but died I hour after birth.
Key Words: Sirenomelia; Vascular anomaly; Congenital heart disease
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