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The Korean Journal of Pathology 1993;27(5): 542-545.
Cellular Blue Nevus: A case report.
Na Hye Myong, Je G Chi, Byung Kyu Cho, Kye Yong Song
1Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
2Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.
3Department of Pathology, College of Medicine, Chung-Ang University, Seoul, Korea.
ABSTRACT
Cellular blue nevus is an benign variant of blue nevus group, characterized by cellular islands composed of closely aggregated spindle cells with little or no melanin. The other variants include atypical and malignant blue nevus which often had the difficulties in the differential diagnosis from the malignant melanoma. A 4-year-old boy presented with hemispheric scalp nodule, which has been slowly grown since birth, measuring 3.5x3x1.5 cm. The surface showed geographic black pigmentation without hairs, hemorrhage, and ulceration. The excised mass disclosed homogeneoulsy dark black, glistening, and muddy cut surface. Histological examination revealed exuberant melanocytic proliferation with both spindle and dendritic components. Heavily pigment ed spindle cells, melanophages, focal necrosis, and vacuolated epithelioid cells were unusually noted in our case and diagnosed as cellular blue nevus. Electron microscopy disclosed largely mature melanosomes in tumor cells and melanophages. During about 16 months since operation, he has been relatively well with no evidence of disease.
Key Words: Cellular blue nevus; Pigmented spindle cells; Epithelioid cells; Melarophage
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