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The Korean Journal of Pathology 1993;27(3): 296-298.
Dedifferentiated Liposarcoma of the Retroperitoneum: A case report.
Woo Sung Moon, Myoung Ja Jeong, Dong Geun Lee, Ho Yeoul Choi, Sang Ho Kim
Department of Pathology, Chonbuk National University College of Medicine, Jeonju, Korea.
We report a case of dedifferentiated liposarcoma of retroperitoneum as a recurrent form in a 41 year old male. The patient received a extirpation for retroperitoneal mass and diagnosed as myxoid liosarcoma 4 years ago. The patient experienced 3 recurrences over a period of 4 years and diagnosed as myxoid liposarcoma in the second, third recurrence also. Histologically, the mass was composed of several clearly distinct elements : well differentiated liposarcoma, myxoid liposarcoma, myxoid malignant fibrous histiocytoma, poorly differntiated sarcoma, and fibrosarcoma. Immunohistochemically, S-100 protein was expressed in the area of spindle cell sarcoma, well differentiated liposarcoma, and malignant fibrous histiocytoma but alpha-1-antichymotrypsin was only expressed in the area of myxoid malignant fibrous histiocytoma.
Key Words: Dedifferentiated liposarcoma; S-100 protein; alpha-1-antichymotrypsin