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The Korean Journal of Pathology 1993;27(3): 287-289.
Pleomorphic Xanthoastrocytoma: A case report.
Soon Ae Oak, Hee Kyung Chang, Man Ha Huh
Department of Pathology, Kosin Medical College, Pusan, Korea.
The Pleomorphic xanthoastrocytoma(PXA) is considered as a special subgroup of gliomas because of its distinctive characteristics: onset in young subject; predilection for the temopral or parietal lobe and a superficial location; frequent appearance as a yellow encapsulated mass with a grossly visible tumor-associated cyst; marked histological pleomorphism; little or no mitosis and no necrosis; presence of a rich reticulin network; and demonstrable GFAP in many of the fusiform and giant cells; most importantly, the relatively favorable prognosis despite plemorphism and bizzare giant cells in the microscopic picture. The objective of this report is to add one more case of pleomorphic xanthoastrocytoma to the medical literature.
Key Words: Pleomorphic xanthoastrocytoma; Pleomorphism; GFAP; Prognosis
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