| Home | E-Submission | Sitemap | Contact Us |  
The Korean Journal of Pathology 1993;27(1): 64-68.
Secretory Meningioma: A case report.
Na Hye Myung, Je G Chi
Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Secretory meningioma is now a distinctive subtype of mostly meningotheliomatous type of meningioma, which was first defined by Alguacil-Garcia et al. It shows characteristic light-microscopic, ultrastructural, and immunohistochemical features of epithelial and secretory differentiation of meningothelial cells with accumulation of secretory material in the from of hyaline inclusions. A 38-year-old female presented with headache for about 5 months. Magnetic resonance imaging revealed a round multilobated mass, measuring 4x4x3 cm, in the right inferior frontal lobe near the skull base, with surrounding brain edema. Histologically, the tumor basically showed a pattern of meningotheliomatous meningioma but tended to deposit eosinophilic homogeneous material both in the intracellular and extracellular spaces. The shape was globular intracellularly and of variable shape and often conglomerated extracellularly. Histochemical stains revealed the material not of psammomatous but of pseudopsammomatous proteinaceous nature. On electron microscopy, there was no intracellular lumen with secretion but granular electron-dense material of variable size accumulated in the degenerated endoplasmic reticulums, suggestive of proteinaceous secretion.
Key Words: Secretory meningioma; Meningothelial; Meningioma; Epithelial differentiation; Hyaline inclusion
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
Related articles
Bile Granuloma Mimicking Peritoneal Seeding: A Case Report  2018 September;52(5)
Secretory Carcinoma Arising in a Fibroadenoma: A Brief Case Report  2018 May;52(3)
Clear Cell Papulosis: A Case Report  2016 September;50(5)
Tailgut Cyst in a Neonate: A Case Report  2016 July;50(4)
Kaposi's Sarcoma -A case report-  1984 December;18(4)