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The Korean Journal of Pathology 1992;26(5): 500-503.
Oxyphilic Clear Cell Carcinoma of the Ovary: A case report.
Chang Won Ha, Jae Soo Koh, Na Hye Myoung, Kyung Ja Cho, Sang Yoon Park, Mi Kyung Kim, Ja June Jang
1Department of Anatiomic Pathology, Korea Cancer Center Hospital, Seoul, Korea.
2Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, Seoul, Korea.
3Department of Pathology, Dankook University College of Medicine, Seoul, Korea.
Oxyphilic clear cell carcinoma of the ovary is a variant of clear cell carcinoma with abundant eosinophilic cytoplasm described by Young & Scully in 1987. Thorough samplin is needed to identify typical foci of clear cell carcinoma for the differential diagnoses from a variety of ovarian tumors with oxyphilic cells. We report a case of oxyphilic clear cell carcinoma in a 65-year-old female patient who presented with vaginal spotting and lower abdominal discomfort. The excised mass was a 10x8x7cm sized, well circumscribe yellowish white solid ovarian tumor. Microscopically, the tumor showed glandular, papillary and alveolar growth patterns composed of cuboidal or hobnail-shaped oxyphilic cells.
Key Words: Carcinoma; Oxyphilic clear cell carcinoma; Ovary; Oxyphilic cell; Clear cell