Oxyphilic Clear Cell Carcinoma of the Ovary: A case report.

Ha,  Chang Won; Koh,  Jae Soo; Myoung,  Na Hye; Cho,  Kyung Ja; Park,  Sang Yoon; Kim,  Mi Kyung; Jang,  Ja June

Case Report

The Korean Journal of Pathology 1992;26(5): 500-503.

Chang Won Ha, Jae Soo Koh, Na Hye Myoung, Kyung Ja Cho, Sang Yoon Park, Mi Kyung Kim, Ja June Jang

¹Department of Anatiomic Pathology, Korea Cancer Center Hospital, Seoul, Korea.
²Department of Obstetrics and Gynecology, Korea Cancer Center Hospital, Seoul, Korea.
³Department of Pathology, Dankook University College of Medicine, Seoul, Korea.

ABSTRACT

Oxyphilic clear cell carcinoma of the ovary is a variant of clear cell carcinoma with abundant eosinophilic cytoplasm described by Young & Scully in 1987. Thorough samplin is needed to identify typical foci of clear cell carcinoma for the differential diagnoses from a variety of ovarian tumors with oxyphilic cells. We report a case of oxyphilic clear cell carcinoma in a 65-year-old female patient who presented with vaginal spotting and lower abdominal discomfort. The excised mass was a 10x8x7cm sized, well circumscribe yellowish white solid ovarian tumor. Microscopically, the tumor showed glandular, papillary and alveolar growth patterns composed of cuboidal or hobnail-shaped oxyphilic cells.

Key Words: Carcinoma; Oxyphilic clear cell carcinoma; Ovary; Oxyphilic cell; Clear cell