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Advances in the Endoscopic Assessment of Inflammatory Bowel Diseases: Cooperation between Endoscopic and Pathologic Evaluations
Jae Hee Cheon
J Pathol Transl Med. 2015;49(3):209-217.   Published online May 15, 2015
DOI: https://doi.org/10.4132/jptm.2015.04.09
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  • 4 Web of Science
  • 4 Crossref
AbstractAbstract PDF
Endoscopic assessment has a crucial role in the management of inflammatory bowel disease (IBD). It is particularly useful for the assessment of IBD disease extension, severity, and neoplasia surveillance. Recent advances in endoscopic imaging techniques have been revolutionized over the past decades, progressing from conventional white light endoscopy to novel endoscopic techniques using molecular probes or electronic filter technologies. These new technologies allow for visualization of the mucosa in detail and monitor for inflammation/dysplasia at the cellular or sub-cellular level. These techniques may enable us to alter the IBD surveillance paradigm from four quadrant random biopsy to targeted biopsy and diagnosis. High definition endoscopy and dye-based chromoendoscopy can improve the detection rate of dysplasia and evaluate inflammatory changes with better visualization. Dye-less chromoendoscopy, including narrow band imaging, iScan, and autofluorescence imaging can also enhance surveillance in comparison to white light endoscopy with optical or electronic filter technologies. Moreover, confocal laser endomicroscopy or endocytoscopy have can achieve real-time histology evaluation in vivo and have greater accuracy in comparison with histology. These new technologies could be combined with standard endoscopy or further histologic confirmation in patients with IBD. This review offers an evidence-based overview of new endoscopic techniques in patients with IBD.

Citations

Citations to this article as recorded by  
  • Colorectal cancer in inflammatory bowel disease: review of the evidence
    D. S. Keller, A. Windsor, R. Cohen, M. Chand
    Techniques in Coloproctology.2019; 23(1): 3.     CrossRef
  • Probe-based confocal laser endomicroscopy in the differential diagnosis of inflammatory bowel diseases: a case series
    Jung Won Park, Tae Il Kim, Jae Hee Cheon
    Intestinal Research.2018; 16(4): 641.     CrossRef
  • How to Assess and Document Endoscopies in IBD Patients by Including Standard Scoring Systems
    Anna M. Buchner, Gary R. Lichtenstein
    Inflammatory Bowel Diseases.2016; 22(4): 1010.     CrossRef
  • Nodular lymphoid hyperplasia: A marker of low-grade inflammation in irritable bowel syndrome?
    Anna Chiara Piscaglia, Lucrezia Laterza, Valentina Cesario, Viviana Gerardi, Rosario Landi, Loris Riccardo Lopetuso, Giovanni Calò, Giovanna Fabbretti, Massimo Brisigotti, Maria Loredana Stefanelli, Antonio Gasbarrini
    World Journal of Gastroenterology.2016; 22(46): 10198.     CrossRef

J Pathol Transl Med : Journal of Pathology and Translational Medicine