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Rare Gastric Lesions Associated with Helicobacter pylori Infection: A Histopathological Review
Mee Joo
J Pathol Transl Med. 2017;51(4):341-351.   Published online June 5, 2017
DOI: https://doi.org/10.4132/jptm.2017.04.03
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  • 13 Web of Science
  • 12 Crossref
AbstractAbstract PDF
Helicobacter pylori infection is associated with chronic gastritis, peptic ulcer disease, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. However, some rare gastric lesions exhibiting distinctive histological features may also be associated with H. pylori infection, including lymphocytic gastritis, granulomatous gastritis, Russell body gastritis, or crystal-storing histiocytosis. Although diverse factors can contribute to their development, there is convincing evidence that H. pylori infection may play a pathogenic role. These findings are mainly based on studies in patients with these lesions who exhibited clinical and histological improvements after H. pylori eradication therapy. Thus, H. pylori eradication therapy might be indicated in patients with no other underlying disease, particularly in countries with a high prevalence of H. pylori infection. This review describes the characteristic histological features of these rare lesions and evaluates the evidence regarding a causative role for H. pylori infection in their pathogenesis.

Citations

Citations to this article as recorded by  
  • Crystal-Storing Histiocytosis: The Iceberg of More Serious Conditions
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    Diagnostics.2023; 13(2): 271.     CrossRef
  • Acute systemic infection-associated Russell body gastroesophagitis: A case report and literature review
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    Human Pathology Reports.2023; 31: 300696.     CrossRef
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    Frontiers in Oncology.2022;[Epub]     CrossRef
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    T.V. Sorokman, P.M. Moldovan, L.Yu. Khlunovska, I.Ya. Lozyuk
    CHILD`S HEALTH.2022; 16(4): 285.     CrossRef
  • Clinicopathological characteristics and aetiological factors of granulomatous gastritis
    Yuanxin Liang, Shengjie Cui, Alexandros D Polydorides
    Histopathology.2021; 79(6): 1040.     CrossRef
  • A case of Russell body gastritis with multifocal lesions
    Michinobu Umakoshi, Ken Miyabe, Hajime Ishii, Yukitsugu Kudo-Asabe, Yukinobu Ito, Makoto Yoshida, Daichi Maeda, Masato Sageshima, Akiteru Goto
    SAGE Open Medical Case Reports.2020; 8: 2050313X2092384.     CrossRef
  • Gastric crystal-storing histiocytosis with concomitant mucosa-associated lymphoid tissue lymphoma
    Mee Joo, Nam-Hoon Kim
    Journal of Pathology and Translational Medicine.2020; 54(4): 332.     CrossRef
  • Nonimmunoglobulin Crystal-Storing Histiocytosis (CSH): Case Report and Literature Review
    Manuel Beltran, Sharad Khurana, Yennifer Gil, Jason T. Lewis, Rohit Kumar, James M. Foran, Masayuki Nagasawa
    Case Reports in Hematology.2020; 2020: 1.     CrossRef
  • Benign and malignant gastroduodenal diseases associated with Helicobacter pylori: a narrative review and personal remarks in 2018
    György M. Buzás
    Minerva Gastroenterologica e Dietologica.2018;[Epub]     CrossRef
  • Crystal-storing Histiocytosis in the Stomach
    Christina A. Arnold, Wendy L. Frankel, Ling Guo, Chandra Krishnan, Sheryl Pfeil, Melinda Schumacher, Lysandra Voltaggio, Martha M. Yearsley, Wei Chen
    American Journal of Surgical Pathology.2018; 42(10): 1317.     CrossRef

J Pathol Transl Med : Journal of Pathology and Translational Medicine