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Case Report
- Immunohistochemical Identification of Pneumocystis jirovecii in Liquid-based Cytology of Bronchoalveolar Lavage: Nine Cases Report.
- Jeong Hyeon Lee, Ji Young Lee, Mi Ran Shin, Hyeong Kee Ahn, Chul Whan Kim, Insun Kim
- Korean J Pathol. 2011;45(1):115-118.
- DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.1.115
- 4,038 View
- 44 Download
- 3 Crossref
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Abstract
PDF - Pneumocystis pneumonia (PCP) is caused by the yeast-like fungus Pneumocystis jirovecii, which is specific to humans. PCP could be a source of opportunistic infection in adults that are immunosuppressed and children with prematurity or malnutrition. The diagnosis should be confirmed by identification of the causative organism, by analysis of the sputum, a bronchoalveolar lavage or a tissue biopsy. In both histologic and cytologic specimens, the cysts are contained within frothy exudates, which form aggregated clumps. The cysts often collapse forming crescent-shaped bodies that resemble ping-pong balls. We recently diagnosed nine cases of PCP using an immunohistochemical stain for Pneumocystis. The patients consisted of five human immunodeficiency virus positive individuals, two renal transplant recipients, and two patients with a malignant disease. All nine patients were infected with P. jirovecii, which was positive for monoclonal antibody 3F6. In conclusion, the immunohistochemical stain used in this report is a new technique for the detection of P. jirovecii infection.
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Citations
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- Metabolic Changes in Serum Metabolome of Beagle Dogs Fed Black Ginseng
Dahye Yoon, Ye Jin Kim, Wan Kyu Lee, Bo Ram Choi, Seon Min Oh, Young Seob Lee, Jae Kwang Kim, Dae Young Lee
Metabolites.2020; 10(12): 517. CrossRef - Effects of Red or Black Ginseng Extract in a Rat Model of Inflammatory Temporomandibular Joint Pain
Hyeon-Jeong Lee, Yun-Kyung Kim, Ja-Hyeong Choi, Jung-Hwa Lee, Hye-Jin Kim, Mi-Gyung Seong, Min-Kyung Lee
Journal of Dental Hygiene Science.2017; 17(1): 65. CrossRef - Value of Bronchoalveolar Lavage Fluid Cytology in the Diagnosis ofPneumocystis jiroveciiPneumonia: A Review of 30 Cases
Ji-Youn Sung, Joungho Han, Young Lyun Oh, Gee Young Suh, Kyeongman Jeon, Taeeun Kim
Tuberculosis and Respiratory Diseases.2011; 71(5): 322. CrossRef
- Metabolic Changes in Serum Metabolome of Beagle Dogs Fed Black Ginseng
Short Case Report
- Pneumocystis jirovecii Pneumonia Accompanied with Fat Embolism: A Case Report.
- Sung Hak Lee, Ok Ran Shin, Eun Jung Lee, Kyo Young Lee
- Korean J Pathol. 2009;43(4):355-357.
- DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.4.355
- 2,915 View
- 24 Download
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Abstract
PDF
- Pneumocystis jirovecii is an atypical fungus that causes severe pneumonia in immune compromised patients. While Pneumocystis jirovecii pneumonia (PCP) is more commonly diagnosed in individuals who have HIV infection, it can occur in individuals with other forms of immunosuppression. Fat embolism most commonly develops after orthopedic injuries, but it has also been reported after other forms of trauma such as severe burns, closed-chest cardiac massage, and liposuction. Overlap in the clinical presentation of these diseases has not yet been reported. We report here on a case of PCP with fat embolism in 52-year-old female patient who had no obvious risk factors for HIV infection. Even if risk factors for HIV or other forms of immunosuppression are not present, PCP can also be seen in patients who present with fat embolism, and the clinical presentation of both conditions can overlap.
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