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Case Reports
Fine Needle Aspiration Cytology of Langerhans Cell Histiocytosis of Mandible: A Case Report.
Sang Ryung Lee, Jae Hee Suh, Hee Jung Cha, Young Min Kim, Hye Jeong Choi
Korean J Pathol. 2010;44(1):106-109.
DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.1.106
  • 3,607 View
  • 23 Download
  • 1 Crossref
AbstractAbstract PDF
We present a case of mandibular involvement with Langerhans cell histiocytosis (LCH), diagnosed by ultrasound-guided aspiration and subsequently confirmed by incisional biopsy and immunohistochemistry in an eight-year-old boy. The cytologic findings included the presence of characteristic Langerhans cells of both mononucleate and multinucleate form. Diagnostic confirmation was obtained by immunopositivity for S-100 protein and CD1a of Langerhans histiocytes on paraffin-embedded sections obtained during incisional biopsy of the right mandibular area. By reporting a case of childhood LCH, we correlate the cytologic findings with histologic features and discuss the role of aspiration cytologic diagnosis in such a rare and cytomorphologically characteristic case.

Citations

Citations to this article as recorded by  
  • Bronchial Washing Cytology of Pulmonary Langerhans Cell Histiocytosis: A Case Report
    Taeyeong Kim, Hyeong Ju Kwon, Minseob Eom, Sang Wook Kim, Min Hi Sin, Soon-Hee Jung
    Journal of Pathology and Translational Medicine.2017; 51(4): 444.     CrossRef
A Case of Desmoplastic Fibroma of the Mandible.
Dong Won Kim, Tae Jung Kwon, Dong Wha Lee
Korean J Pathol. 1988;22(3):340-347.
  • 1,638 View
  • 15 Download
AbstractAbstract PDF
A case of desmoplastic fibroma of mandible in a 18 years old woman is presented. She had complained progressive swelling of right mandible for 4 years. Radiographically, a multilocular radiolucent of right hemimandibulectomy showed multinodular external surface without cortical destruction. Cut surfaces revealed grayish white, fibrous homogeneous appearance with firm consistency, sparing head portion. The maximum diameter of the tumor was 13 cm. Microscopically, the tumor was composed of interlacing bundles of monomorphic spindle-shaped cells with abundant intercellular collagen. Ultrastructurally, most tumor cells were fibroblastic-like cells with abundant RER and cytoplasmic fibrils, but a few disclosed transition to myofibroblasts. However, no fully developed myofibroblasts were seen.

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