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1 "Intranuclear Inclusions"
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Case Report
The Cytologic Features of Desmoplastic Small Round Cell Tumor with Intranuclear Inclusions : A Case Report .
Ho Chang Lee, Hye Suk Han, Ok Jun Lee
Korean J Pathol. 2009;43(3):279-284.
DOI: https://doi.org/10.4132/KoreanJPathol.2009.43.3.279
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Desmoplastic small round cell tumor (DSRCT) is a rare neoplasm of young adults and it is characterized by polyphenotypic differentiation. We experienced a case of abdominal DSRCT that occurred in a 19-year-old female who presented with painful swelling of her right forearm. The tumor was cytokeratin-negative and it exhibited some tumor cells with intranuclear inclusions. Molecular demonstration of EWS-WT1 fusion transcripts is particularly useful to confirm the diagnosis of DSRCT without epithelial differentiation. We report here on a case of cytokeratin-negative DSRCT that showed an unusual feature of intranuclear inclusions.

J Pathol Transl Med : Journal of Pathology and Translational Medicine
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