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- Diagnostic conundrums of schwannomas: two cases highlighting morphological extremes and diagnostic challenges in biopsy specimens of soft tissue tumors
- Chankyung Kim, Yang-Guk Chung, Chan Kwon Jung
- J Pathol Transl Med. 2023;57(5):278-283. Published online August 24, 2023
- DOI: https://doi.org/10.4132/jptm.2023.07.13
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- 3 Web of Science
- 4 Crossref
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Abstract
PDF - Schwannomas are benign, slow-growing peripheral nerve sheath tumors commonly occurring in the head, neck, and flexor regions of the extremities. Although most schwannomas are easily diagnosable, their variable morphology can occasionally create difficulty in diagnosis. Reporting pathologists should be aware that schwannomas can exhibit a broad spectrum of morphological patterns. Clinical and radiological examinations can show correlation and should be performed, in conjunction with ancillary tests, when appropriate. Furthermore, deferring a definitive diagnosis until excision may be necessary for small biopsy specimens and frozen sections. This report underscores these challenges through examination of two unique schwannoma cases, one predominantly cellular and the other myxoid, both of which posed significant challenges in histological interpretation.
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Citations
Citations to this article as recorded by
- Oral and maxillofacial schwannoma (OMSCH): An institutional study of 102 patients
Lingli Huang, Wenya Zhu, Qicheng Ye, Shengwen Liu, Hao Lu, Wenjun Yang, Wanlin Xu
Journal of Stomatology Oral and Maxillofacial Surgery.2026; 127(3): 102678. CrossRef - Plexiform Schwannoma Over the Anterior Chest Wall: A Clinicopathological Review
Debojyoti Sasmal, Saswata Barenya, Hinglaj Saha, Pankaj Kumar Halder
Amrita Journal of Medicine.2025; 21(2): 95. CrossRef - Giant Retroperitoneal Schwannoma: Case Report and Review of the Literature
Magdalena Alexieva, Evgeni V Mekov, Silvia Ivanova, Alexandrina Vlahova, Georgi Yankov
Cureus.2025;[Epub] CrossRef - Breast schwannoma: review of entity and differential diagnosis
Sandra Ixchel Sanchez, Ashley Cimino-Mathews
Journal of Pathology and Translational Medicine.2025; 59(6): 353. CrossRef
- Oral and maxillofacial schwannoma (OMSCH): An institutional study of 102 patients
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