Journal of Pathology and Translational Medicine

Young Sub Lee

3 Articles

Primary Neurilemmoma of the Thyroid Gland Clinically Mimicking Malignant Thyroid Nodule: Young Sub Lee, Jee Soon Kim, Arthur Minwoo Chung, Woo Chan Park, Tae-Jung Kim; J Pathol Transl Med. 2016;50(2):168-171. Published online October 26, 2015; DOI: https://doi.org/10.4132/jptm.2015.08.26

8,623 View
71 Download
1 Web of Science
5 Crossref

PDF

Citations

Citations to this article as recorded by

Rapidly Growing Thyroid Schwannoma: Diagnostic Challenges and Management Strategies
Freddy J K Toloza, Armando Filie, Mark Raffeld, Electron Kebebew, Joanna Klubo-Gwiezdzinska, Sriram Gubbi
JCEM Case Reports.2025;[Epub] CrossRef
Primary schwannoma of the thyroid gland: analysis of case characteristics and review of the literature
Hangjun Ren, Xingguo Cui, Lianmei Zhang
BMC Surgery.2024;[Epub] CrossRef
A Case of Intra-thyroidal Schwannoma Diagnosed by Preoperative Core Needle Biopsy
Dong Gyu Choi, Young-Ok Kim, Min Jung Jung, Hyoung Shin Lee
Korean Society for Head and Neck Oncology.2023; 39(1): 37. CrossRef
Multimodal ultrasound imaging of primary thyroid schwannoma
Hai Na Zhao, Bu Yun Ma, Feng Yan, Yu Lan Peng
Medicine.2021; 100(16): e25517. CrossRef
A Case of Anterior Cervical Intramuscular Schwannoma in the Strap Muscle
Seul Gi Lee, Ho-Ryun Won, Bon Seok Koo, Jae Won Chang
Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2021; 64(4): 263. CrossRef

Histologic Disorderliness in the Arrangement of Tumor Cells as an Objective Measure of Tumor Differentiation: Sungwook Suh, Gyeongsin Park, Young Sub Lee, Yosep Chong, Youn Soo Lee, Yeong Jin Choi; Korean J Pathol. 2014;48(5):339-345. Published online October 27, 2014; DOI: https://doi.org/10.4132/KoreanJPathol.2014.48.5.339

6,681 View
66 Download

Abstract PDF: Background: Inter-observer and intra-observer variation in histologic tumor grading are well documented. To determine whether histologic disorderliness in the arrangement of tumor cells may serve as an objective criterion for grading, we tested the hypothesis the degree of disorderliness is related to the degree of tumor differentiation on which tumor grading is primarily based. Methods: Borrowing from the statistical thermodynamic definition of entropy, we defined a novel mathematical formula to compute the relative degree of histologic disorderliness of tumor cells. We then analyzed a total of 51 photomicrographs of normal colorectal mucosa and colorectal adenocarcinoma with varying degrees of differentiation using our formula. Results: A one-way analysis of variance followed by post hoc pairwise comparisons using Bonferroni correction indicated that the mean disorderliness score was the lowest for the normal colorectal mucosa and increased with decreasing tumor differentiation. Conclusions: Disorderliness, a pathologic feature of malignant tumors that originate from highly organized structures is useful as an objective tumor grading proxy in the field of digital pathology.

Classic Papillary Thyroid Carcinoma with Tall Cell Features and Tall Cell Variant Have Similar Clinicopathologic Features: Woo Jin Oh, Young Sub Lee, Uiju Cho, Ja Seong Bae, Sohee Lee, Min Hee Kim, Dong Jun Lim, Gyeong Sin Park, Youn Soo Lee, Chan Kwon Jung; Korean J Pathol. 2014;48(3):201-208. Published online June 26, 2014; DOI: https://doi.org/10.4132/KoreanJPathol.2014.48.3.201

17,810 View
169 Download
37 Crossref

Abstract PDF

Background

The tall cell variant of papillary thyroid carcinoma (TCVPTC) is more aggressive than classic papillary thyroid carcinoma (PTC), but the percentage of tall cells needed to diagnose TCVPTC remains controversial. In addition, little is known about the clinicopathologic features of classic PTC with tall cell features (TCF).

Methods

We retrospectively selected and reviewed the clinicopathologic features and presence of the BRAF mutation in 203 cases of classic PTC, 149 cases of classic PTC with TCF, and 95 cases of TCVPTCs, which were defined as PTCs having <10%, 10-50%, and ≥50% tall cells, respectively.

Results

TCVPTCs and classic PTCs with TCF did not vary significantly in clinicopathologic characteristics such as pathologic (p) T stage, extrathyroidal extension, pN stage, lateral lymph node metastasis, or BRAF mutations; however, these features differed significantly in TCVPTCs and classic PTCs with TCF in comparison to classic PTCs. Similar results were obtained in a subanalysis of patients with microcarcinomas (≤1.0 cm in size).

Conclusions

Classic PTCs with TCF showed a similar BRAF mutation rate and clinicopathologic features to TCVPTCs, but more aggressive characteristics than classic PTCs.

Citations

Citations to this article as recorded by

External validation of a deep learning-based algorithm for detection of tall cells in papillary thyroid carcinoma: A multicenter study
Sebastian Stenman, Sylvain Bétrisey, Paula Vainio, Jutta Huvila, Mikael Lundin, Nina Linder, Anja Schmitt, Aurel Perren, Matthias S. Dettmer, Caj Haglund, Johanna Arola, Johan Lundin
Journal of Pathology Informatics.2024; 15: 100366. CrossRef
Focal Tall Cell Change in Papillary Thyroid Carcinoma: Lessons Learned from Practices Adopting Rigid Criteria (Height to Width Ratio of 3)
Esther Diana Rossi, Liron Pantanowitz
Endocrine Pathology.2024; 35(1): 80. CrossRef
Predicting tall-cell subtype of papillary thyroid carcinomas independently with preoperative multimodal ultrasound
Bei-Bei Ye, Yun-Yun Liu, Ying Zhang, Bo-Ji Liu, Le-Hang Guo, Qing Wei, Yi-Feng Zhang, Hui-Xiong Xu
British Journal of Radiology.2024; 97(1159): 1311. CrossRef
TERT mutations and aggressive histopathologic characteristics of radioiodine-refractory papillary thyroid cancer
Ju Yeon Pyo, Yoon Jin Cha, SoonWon Hong
Journal of Pathology and Translational Medicine.2024; 58(6): 310. CrossRef
Papillary Thyroid Carcinomas with Tall Cell Features: An Intermediate Entity Between Classic and Tall Cell Subtypes
Athanasios Bikas, Kristine Wong, Theodora Pappa, Sara Ahmadi, Craig B. Wakefield, Ellen Marqusee, Pingping Xiang, Benjamin Altshuler, Jacob Haase, Justine A. Barletta, Iñigo Landa, Erik K. Alexander
Thyroid.2023; 33(6): 697. CrossRef
A novel nomogram for identifying high-risk patients among active surveillance candidates with papillary thyroid microcarcinoma
Li Zhang, Peisong Wang, Kaixuan Li, Shuai Xue
Frontiers in Endocrinology.2023;[Epub] CrossRef
The Impact of BRAF V600E Mutation Allele Frequency on the Histopathological Characteristics of Thyroid Cancer
Mawaddah Abdulhaleem, Saruchi Bandargal, Marc Philippe Pusztaszeri, Mohannad Rajab, Hannah Greenspoon, Joshua Ross Krasner, Sabrina Daniela Da Silva, Véronique-Isabelle Forest, Richard J. Payne
Cancers.2023; 16(1): 113. CrossRef
Protruding Huge Thyroid Mass Concurrent Hemorrhage and Skin Necrosis: A Case Report
Solji An, Joonseon Park, Kwangsoon Kim, Ja Seong Bae, Jeong Soo Kim
Journal of Endocrine Surgery.2023; 23(4): 143. CrossRef
CD56 Expression in Papillary Thyroid Carcinoma Is Highly Dependent on the Histologic Subtype: A Potential Diagnostic Pitfall
Uiju Cho, Yourha Kim, Sora Jeon, Chan Kwon Jung
Applied Immunohistochemistry & Molecular Morphology.2022; 30(5): 389. CrossRef
Aggressive histopathological variants of papillary thyroid carcinoma, diagnostic challenge, and clinical significance—A case series
PK Pravanya, KR Anila, Shaji Thomas, A Sreekumar, K Jayasree
Medical Journal of Dr. D.Y. Patil Vidyapeeth.2022; 15(6): 922. CrossRef
Tall cell variant papillary thyroid carcinoma impacts disease-free survival at the 10 % cut-point on multivariate analysis
Shabnam Samankan, Leah Militello, Gabriella Seo, Sedef Everest, Quinn O'Malley, Sarah L. Spaulding, Monica Xing, Ammar Matloob, John Beute, Raymond Chai, Scott Doyle, Mark L. Urken, Margaret Brandwein-Weber
Pathology - Research and Practice.2022; 236: 154012. CrossRef
A population-based study of the three major variants of papillary thyroid carcinoma
Junming Xu, Yingying Zhang, Jun Liu, Shenglong Qiu, Min Wang
Journal of International Medical Research.2021;[Epub] CrossRef
Tall cell percentage alone in PTC without aggressive features should not guide patients’ clinical management
Anello Marcello Poma, David Viola, Elisabetta Macerola, Agnese Proietti, Eleonora Molinaro, Dario De Vietro, Rossella Elisei, Gabriele Materazzi, Paolo Miccoli, Fulvio Basolo, Clara Ugolini
The Journal of Clinical Endocrinology & Metabolism.2021; 106(10): e4109. CrossRef
Molecular Pathology of Non-familial Follicular Epithelial–Derived Thyroid Cancer in Adults: From RAS/BRAF-like Tumor Designations to Molecular Risk Stratification
Paula Soares, Antónia Afonso Póvoa, Miguel Melo, João Vinagre, Valdemar Máximo, Catarina Eloy, José Manuel Cameselle-Teijeiro, Manuel Sobrinho-Simões
Endocrine Pathology.2021; 32(1): 44. CrossRef
Deep Neck Infection: Atypical Presentation of Papillary Thyroid Cancer
Apichana Mahattanapreut, Rangsima Aroonroch, Chalermchai Chintrakarn, Chutintorn Sriphrapradang, Dinesh K. Chhetri
Case Reports in Otolaryngology.2021; 2021: 1. CrossRef
The evolving concept of aggressive histological variants of differentiated thyroid cancer
Juan C. Hernandez-Prera
Seminars in Diagnostic Pathology.2020; 37(5): 228. CrossRef
Papillary Thyroid Cancer—Aggressive Variants and Impact on Management: A Narrative Review
Andrés Coca-Pelaz, Jatin P. Shah, Juan C. Hernandez-Prera, Ronald A. Ghossein, Juan P. Rodrigo, Dana M. Hartl, Kerry D. Olsen, Ashok R. Shaha, Mark Zafereo, Carlos Suarez, Iain J. Nixon, Gregory W. Randolph, Antti A. Mäkitie, Luiz P. Kowalski, Vincent Van
Advances in Therapy.2020; 37(7): 3112. CrossRef
Contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma
Sara Cartwright, Abbey Fingeret
Current Opinion in Endocrinology, Diabetes & Obesity.2020; 27(5): 351. CrossRef
Le carcinome papillaire de la thyroïde avec contingent à cellules hautes : facteurs pronostiques
I. Riahi, H. Jaafoura, H. Saibi, E. Chebil, I. Ben Nacef, M. Ksentini, T. Ben Ghachem, R. Lahiani, M. Ben Salah
Annales d'Endocrinologie.2020; 81(4): 345. CrossRef
Updates in the Pathologic Classification of Thyroid Neoplasms: A Review of the World Health Organization Classification
Yanhua Bai, Kennichi Kakudo, Chan Kwon Jung
Endocrinology and Metabolism.2020; 35(4): 696. CrossRef
Tall Cell Variant of Papillary Thyroid Carcinoma: Impact of Change in WHO Definition and Molecular Analysis
Kristine S. Wong, Sara E. Higgins, Ellen Marqusee, Matthew A. Nehs, Trevor Angell, Justine A. Barletta
Endocrine Pathology.2019; 30(1): 43. CrossRef
Histopatological and molecular genetic characteristics of clinically aggressive variants of papillary thyroid carcinoma
A. V. Bogolyubova, A. Yu. Abrosimov, L. S. Selivanova, P. V. Belousov
Arkhiv patologii.2019; 81(1): 46. CrossRef
Papillary Thyroid Cancers with Focal Tall Cell Change are as Aggressive as Tall Cell Variants and Should Not be Considered as Low-Risk Disease
Pim J. Bongers, Wouter P. Kluijfhout, Raoul Verzijl, Mattan Lustgarten, Marloes Vermeer, David P. Goldstein, Karen Devon, Lorne E. Rotstein, Sylvia L. Asa, James D. Brierley, Richard W. Tsang, Shereen Ezzat, Menno R. Vriens, Ozgur Mete, Jesse D. Pasternak
Annals of Surgical Oncology.2019; 26(8): 2533. CrossRef
A case-based approach to aggressive variants of papillary thyroid carcinoma with literature review
JosephAntoine Flordelis Chatto, AnnetteLaurente Salillas
Thyroid Research and Practice.2019; 16(3): 128. CrossRef
Clinically Relevant Prognostic Parameters in Differentiated Thyroid Carcinoma
Tyler Janovitz, Justine A. Barletta
Endocrine Pathology.2018; 29(4): 357. CrossRef
Prediction of novel target genes and pathways involved in tall cell variant papillary thyroid carcinoma
Fada Xia, Bo Jiang, Yong Chen, Xin Du, Yao Peng, Wenlong Wang, Zhuolu Wang, Xinying Li
Medicine.2018; 97(51): e13802. CrossRef
Papillary thyroid carcinoma with tall cell features is as aggressive as tall cell variant: a meta-analysis
Huy Gia Vuong, Nguyen Phuoc Long, Nguyen Hoang Anh, Tran Diem Nghi, Mai Van Hieu, Le Phi Hung, Tadao Nakazawa, Ryohei Katoh, Tetsuo Kondo
Endocrine Connections.2018; 7(12): R286. CrossRef
TERT Promoter Mutation in an Aggressive Cribriform Morular Variant of Papillary Thyroid Carcinoma
Eun Ji Oh, Sohee Lee, Ja Seong Bae, Yourha Kim, Sora Jeon, Chan Kwon Jung
Endocrine Pathology.2017; 28(1): 49. CrossRef
Update on the cytologic features of papillary thyroid carcinoma variants
Marc Pusztaszeri, Manon Auger
Diagnostic Cytopathology.2017; 45(8): 714. CrossRef
Molecular correlates and rate of lymph node metastasis of non-invasive follicular thyroid neoplasm with papillary-like nuclear features and invasive follicular variant papillary thyroid carcinoma: the impact of rigid criteria to distinguish non-invasive f
Uiju Cho, Ozgur Mete, Min-Hee Kim, Ja Seong Bae, Chan Kwon Jung
Modern Pathology.2017; 30(6): 810. CrossRef
BRAF-positive paucicellular variant of anaplastic carcinoma in the presence of tall cell variant papillary thyroid cancer
O. V. Dolzhansky, E. M. Paltseva, D. N. Khmelkova, F. A. Konovalov, I. V. Kanivets, A. V. Lavrov, D. V. Pyankov, S. A. Korostelev, O. A. Levendyuk, V. M. Pominalnaya, D. N. Fedorov
Arkhiv patologii.2017; 79(3): 27. CrossRef
A comparison of the clinicopathological features and prognoses of the classical and the tall cell variant of papillary thyroid cancer: a meta-analysis
Zeming Liu, Wen Zeng, Tianwen Chen, Yawen Guo, Chao Zhang, Chunping Liu, Tao Huang
Oncotarget.2017; 8(4): 6222. CrossRef
Clinical utility of TERT promoter mutations and ALK rearrangement in thyroid cancer patients with a high prevalence of the BRAF V600E mutation
Ja Seong Bae, Yourha Kim, Sora Jeon, Se Hee Kim, Tae Jung Kim, Sohee Lee, Min-Hee Kim, Dong Jun Lim, Youn Soo Lee, Chan Kwon Jung
Diagnostic Pathology.2016;[Epub] CrossRef
Tall cell variant of papillary thyroid carcinoma: current evidence on clinicopathologic features and molecular biology
Xiaofei Wang, Wenli Cheng, Chongqing Liu, Jingdong Li
Oncotarget.2016; 7(26): 40792. CrossRef
The Warthin-Like Variant of Papillary Thyroid Carcinoma: A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis
Min-kyung Yeo, Ja Seong Bae, Sohee Lee, Min-Hee Kim, Dong-Jun Lim, Youn Soo Lee, Chan Kwon Jung
International Journal of Endocrinology.2015; 2015: 1. CrossRef
BRAF Immunohistochemistry Using Clone VE1 is Strongly Concordant with BRAFV600E Mutation Test in Papillary Thyroid Carcinoma
Jung-Soo Pyo, Jin Hee Sohn, Guhyun Kang
Endocrine Pathology.2015; 26(3): 211. CrossRef
Pathologie de la thyroïde. Cas no 3. Carcinome papillaire de la thyroïde, variante à cellules hautes
Emmanuelle Leteurtre
Annales de Pathologie.2015; 35(5): 402. CrossRef

Author index