- Secretory Carcinoma Arising in a Fibroadenoma: A Brief Case Report
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Sharon Lim, Min Keun Shim, Eun Yoon Cho, Soo Youn Cho
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J Pathol Transl Med. 2018;52(3):198-201. Published online October 4, 2017
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DOI: https://doi.org/10.4132/jptm.2017.08.01
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- Breast Carcinoma within Fibroadenoma: A Systematic Review
Abdulwahid M. Salih, Lana R.A. Pshtiwan, Mohammed Gh. Hamasaeed, Sami S. Omar, Shaban Latif, Shadi H. Sidiq, Bushra O. Hussein, Hunar A. Hassan, Diyar A. Omar, Sarhang S. Abdalla, Hemn A. Hassan, Yousif M. Mahmood, Marwan N. Hassan, Dahat A. Barw Medical Journal.2024;[Epub] CrossRef
- Significance of Parafibromin Expression in Laryngeal Squamous Cell Carcinomas
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Inju Cho, Mija Lee, Sharon Lim, Ran Hong
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J Pathol Transl Med. 2016;50(4):264-269. Published online June 23, 2016
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DOI: https://doi.org/10.4132/jptm.2016.04.24
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Abstract
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- Background
Parafibromin is a product of the tumor suppressor gene that has been studied as a potential indicator of tumor aggressiveness in the parathyroid, breast, colorectum, and stomach. However, the clinical significance and potential function of parafibromin expression in head and neck squamous cell carcinomas remain largely unknown. The aim of this study was to evaluate the expression of parafibromin in laryngeal squamous cell carcinoma (LSCC) and to verify its potential as a biomarker of tumor behavior.
Methods Parafibromin expression was evaluated in 30 cases of LSCC using immunohistochemistry. The correlations between parafibromin expression and clinicopathologic parameters were investigated.
Results Parafibromin expression was positive in 15 cases (50%) and negative in 15 cases (50%). Tumor size and T stage showed a statistically significant inverse relationship with parafibromin expression (p=.028 and p<.001, respectively). Parafibromin expression was not associated with age, sex, lymph node metastasis, tumor differentiation, or tumor location. There was no statistically significant relationship between parafibromin expression and progression-free survival in the patients (p>.05).
Conclusions Our results indicate that the downregulation or loss of parafibromin expression can be employed as a novel marker of tumor progression or aggressiveness in LSCC.
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CDC73 c.1155-3A>G is a pathogenic variant that causes aberrant splicing, disrupted parafibromin expression, and hyperparathyroidism-jaw tumor syndrome
Leor Needleman, Nicolette Chun, Sathvika Sitaraman, Marilyn Tan, Deborah E Sellmeyer, Electron Kebebew, Justin P Annes JBMR Plus.2024;[Epub] CrossRef - Advances in the application of labelāfree quantitative proteomics techniques in malignancy research
Xiao Meng, Dong Liu, Yan Guan Biomedical Chromatography.2023;[Epub] CrossRef - The roles of the tumor suppressor parafibromin in cancer
Hua-chuan Zheng, Hang Xue, Cong-yu Zhang Frontiers in Cell and Developmental Biology.2022;[Epub] CrossRef - The clinicopathological and prognostic significances of CDC73 expression in cancers: a bioinformatics analysis
Hua-Chuan Zheng, Bao-Cheng Gong, Shuang Zhao Oncotarget.2017; 8(56): 95270. CrossRef
- Digital Papillary Carcinoma
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Sharon Lim, Inju Cho, Mi Ja Lee
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Korean J Pathol. 2014;48(6):438-441. Published online December 31, 2014
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DOI: https://doi.org/10.4132/KoreanJPathol.2014.48.6.438
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9,022
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- Digital Papillary Adenocarcinoma: Uncommon Malignancy of Sweat Glands - Two Rare Cases
Neeti Goyal, Pawan Dhaman, Jasvinder Kaur Bhatia, Pragya Sharma, Prabha Shankar Mishra, Vikram Singh, Anvesh Rathore Journal of Marine Medical Society.2025; 27(1): 103. CrossRef - Digital papillary adenocarcinoma: A case report of a rare malignant tumour with recommendations on management and follow-up
Varanindu Mudduwa, Mohammad Goodarzi, Richard Chalmers, Haitham Khashaba International Journal of Surgery Case Reports.2025; 127: 110922. CrossRef - Digital papillary adenocarcinoma: A case report
Betty A. Kasimo, Vivian Akello, James J. Yahaya Clinical Case Reports.2021;[Epub] CrossRef - A rare case of a digital papillary carcinoma of the hand with secondary conservative management
Rabeet Khan, Renu Irri, Effie Katsarma Journal of Surgical Case Reports.2020;[Epub] CrossRef
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