- Spindle cell oncocytoma of the sella turcica with anaplastic features and rapid progression in short-term follow-up: a case report with proposal of distinctive radiologic features
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Dong Ja Kim, SangHan Lee, Mee-seon Kim, Jeong-Hyun Hwang, Myong Hun Hahm
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J Pathol Transl Med. 2021;55(3):225-229. Published online March 9, 2021
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DOI: https://doi.org/10.4132/jptm.2021.01.27
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- We present a rare case of spindle cell oncocytoma (SCO) of the sella turcica with malignant histologic features and rapid progression. A 42-year-old woman experienced bilateral blurred vision and was preoperatively misdiagnosed as having a pituitary macroadenoma on magnetic resonance imaging. After surgery, SCO was diagnosed by the histopathologic features of interlacing fascicles of spindle tumor cells with finely granular, eosinophilic cytoplasm. Focal anaplastic changes and necrosis were present. Immunohistochemically, the tumor cells were positive for vimentin, epithelial membrane antigen, S-100, galectin-3, and thyroid transcription factor 1. Four months later, the tumor had progressed, and second surgery with adjuvant radiotherapy was performed; the patients remains under observation. In this report, we proposed distinctive radiologic features for differential diagnosis between SCO and other pituitary tumors.
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Citations
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- Pituitary Spindle Cell Oncocytoma: More than a Grade 1 Tumor?
Jonathan Hammond, Zacharie Gagne, Bojana Mitrovic, Stefano M. Priola Neurology International.2025; 17(2): 16. CrossRef - Treatment modalities and outcomes of granular cell tumors and spindle cell oncocytomas of the pituitary gland: an analysis of two national cancer databases
A. Yohan Alexander, Giorgos Michalopoulos, Panagiotis Kerezoudis, Jamie J. Van Gompel, Michael J. Link, Maria Peris-Celda Acta Neurochirurgica.2024;[Epub] CrossRef - Spindle cell oncocytoma, a misdiagnosed rare entity of the pituitary – A case report with review of literature and special emphasis on the morphological differentials
Gittwa Vatsaraj Kottangal, Lilly Madhavan, Shalini Kuruvilla, Kavitha Kanjirakadu Parameswaran, Shehla Basheer Kollathodi Indian Journal of Pathology and Oncology.2021; 8(4): 533. CrossRef
- Sudden Child Death due to Thrombotic Giant Coronary Artery Aneurysms Complicated by Atypical Kawasaki Disease: An Autopsy Case
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DongJa Kim, Man-Hoon Han, SangHan Lee
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J Pathol Transl Med. 2018;52(4):248-251. Published online May 11, 2018
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DOI: https://doi.org/10.4132/jptm.2017.10.23
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- Autopsy report of a sudden infant death that was strongly suspicious of Kawasaki disease
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