- A Histopathologic Study on Tumors of Upper Respiratory Tract
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Geung Hwan Ahn
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Korean J Cytopathol. 1970;4(1):35-44.
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 Abstract
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- A histopathologic study was made on 436 cases of tumors of upper respiratory tract, which were obtained during a period of 10 years, from 1959 to 1968, at the Department of Pathology, College of Medicine, Seoul National University, and the results were as follow;
1. Four hundred and thirty-six tumors of upper respiratory tract examined consist of 96 (22%) benign and 340 (78%) malignant tumors.
2. Among all tumors of upper respiratory tract, their site incidence by the frequency ratio is highest for tumors of larynx (34.9%), and, thereafter, in order of frequency ratio, for tumors of nasal cavity (22.0%), tumors of pharynx (12.6%), tumors of nasopharynx (9.6%) and tumor of trachea (0.2%).
3. The age distribution of all benign tumors of upper respiratory tract showed highest incidence (25.1%) in the third decade with mean age of 33.1 years. The age distribution of all malignant tumors of upper respiratory tract showed highest incidence (33.5%) in sixth decade with mean age of 49.6 years.
4. Ninety-six benign and 340 malignant tumors of upper respiratory tract were histologically classified and tabulated. Among benign tumors, squamous cell papilloma, hemangioma and fibroma were especially prevalent, and among malignant tumors, squamous cell carcinoma, undifferentiated carcinoma and lymphosarcoma were more commonly encountered.
5. Site, sex and age distribution of 436 tumors of upper respiratory tract were tabulated, and some tumors were selected and described in detail.
- Congenital Cystic Lung -An Autopsy Case Report of a Congenital cystic Lung associated with Hydramnios-
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Geung Hwan Ahn, Yong II Kim, Sang In Kim, Sang Kook Lee, Hae Sook Yun, Jung Eun Mok
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Korean J Cytopathol. 1969;3(1):21-25.
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- A case of congenital cystic disease of middle and lower lobe of right lung in premature female infant delivered at 8 months of gestation is reported.
The congenital cystic disease is relatively rare malformation.
Hydramnios and anasarca in the newborn infant were present and the cysts were lined by bronchial epithelium.
These clinicopathological findings are compatible with that of the case reported by Ch’in and Tang in 1949.
Embryologically the condition is of the nature of a malformation which starts when lung anlage had already undergone lobulation but cartilage, arteries, mucous glands and alveoli are not yet differentiated.
- Congenital Endocardial Fibro-elastosis
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Je G. Chi, Geung Hwan Ahn, Sang Woo Kim, Sang Kook Lee
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Korean J Cytopathol. 1969;3(1):27-31.
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- An autopsy case of congenital endocardial fibro-elastosis in a newborn infant is described. The patient revealed acute fatal type of heart failure sixty-two days after the birth. Autopsy revealed grayish white mural thickening in the left ventricle, and this change also involved the mitral valvular structure showing irregular shortening and thickening. No evidence of other intra-cardiac malformation was present. Microscopically, the mural thickening consisted of exuberant proliferation of fibrous tissue as well as the elastic fibers. There were encountered scattered foci of small round cell infiltration in the thickened endocardium and subendocardial spaces.
- Congenital Sacro-Coccygeal Teratoma (Report of an Autopsy Case)
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Moon Ho Yang, Joong Hee Lee, Geung Hwan Ahn, Je G. Chi, Sang Kook Lee
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Korean J Cytopathol. 1969;3(1):33-37.
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- An autopsy case of a congenital sacrococcygeal teratoma in a dead born fetus of eight months gestation is reported. The fetus weighs 1.3 kg. and reveals a large protruding tumor mass in sacral region, measuring 14×10×10 cm. and weighing 400 gm. The tumor is completely covered with skin. The tumor masses are partly cystic and partly solid with variegated appearance on cut sections. Anteriorly the tumor is partly extending into spinal canal.
Microscopically the tumor is composed of various elements derived from trigerm layers. Most prominent elements are central nervous tissue with considerable amount of choroidal plexus. No evidence of malignancy is noted.
There are found no congenital anomalies except for the teratoma.
Brief review of literature is made.
- A histopathologic Study of 35 congenital Neck Cysts
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Geung Hwan Ahn, Je Geun Chi, Jae Young Lee, Eui Keun Ham, Sang Kook Lee
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Korean J Cytopathol. 1968;2(2):135-141.
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- A histopathologic observation of 35 congenital cysts of the neck (19 branchial cysts and 16 thyroglossal duct cysts) obtained during a period of 10 years, 1958 to 1967, at the department of pathology, College of Medicine, Seoul National University, is presented.
The sex ratio of male and female of branchial cyst was 8: 11.
The age distribution of branchial cysts showed the highest frequency in the decade of 21-30 (36.9%) and also considerably high frequencies in the decade of 11-20(31.5%). Branchial cysts were usually located along theanterior border of the sternocleidomastoid muscle and above or below the sternocleidomastoid muscle in the lateral aspect of the neck.
Microscopically there observed stratified squamous epithelial linings in 68.4% of the total cases and lymphoid tissues in 89.5%, among which sinusoids are noted in 78.9% of the cases.
The sex ratio of male and female of thyroglossal duct cyst was 3:5. The age distribution of the thyroglossal duct cyst showed the highest frequency in the decade of 0-10(31.3%) and also considerably high frequency in the decade 21-30 (25.0%).
The thyroglossal duct cysts were usually located in the median portion of the anterior aspect of the neck.
Microscopical1y stratified squamous linings are observed in 37.5% of the cases and pseudostratified ciliated columnar in 31.3%. No lymphoid tissues are reserved and there are noted normal thyroid follicles in the cyst wall in 37.5% of the cases.
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