- Unusual Histology of Eosinophilic Myenteric Ganglionitis: A Case Report
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Hyekyung Lee, Dongwook Kang, Heejin Kim, Byungsun Cho, Jeho Jang
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J Pathol Transl Med. 2017;51(3):320-324. Published online April 4, 2017
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DOI: https://doi.org/10.4132/jptm.2016.09.07
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- Eosinophilic myenteric ganglionitis is a disorder characterized by infiltration of the Auerbach myenteric plexus by eosinophils. As a cause of chronic intestinal pseudo-obstruction (CIPO), eosinophilic myenteric ganglionitis has been rarely reported and the majority of the reported cases in the literature were children. We experienced a case of eosinophilic myenteric ganglionitis associated with CIPO in a 53-year-old female patient. Histologic examination of the resected descending colon showed moderate eosinophilic infiltrates with hypogangliosis in the myenteric plexus. Immunohistochemical study revealed increased number of CD4-positive lymphocytes and stronger but scantier glial fibillary acid protein expression in the inflamed myenteric plexus.
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Citations
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