Journal of Pathology and Translational Medicine

Ah-Young Kwon

2 Articles

Cytologic Characteristics of Thymic Adenocarcinoma with Enteric Differentiation: A Study of Four Fine-Needle Aspiration Specimens: Ah-Young Kwon, Joungho Han, Hae-yon Cho, Seokhwi Kim, Heejin Bang, Jiyeon Hyeon; J Pathol Transl Med. 2017;51(5):509-512. Published online August 4, 2017; DOI: https://doi.org/10.4132/jptm.2017.03.22

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Thymic adenocarcinoma is extremely rare. Although its histologic features have been occasionally reported, a lack of description of the cytologic features has hampered the prompt and accurate diagnosis of this condition. Herein, we describe the cytologic findings and histology of four aspiration cytology specimens of thymic adenocarcinoma. The specimens were obtained from primary tumors, metastatic lymph nodes, and pericardial effusions. All four specimens showed three-dimensional glandular clusters with a loss of polarity and nuclear overlapping. One specimen had extensive extracellular mucinous material. Three specimens contained tumor cells with intracytoplasmic vacuoles. While the specimen with extracellular mucin showed relatively mild cytologic atypia, other specimens exhibited more atypical cytologic changes: irregular nuclear membranes, a coarse chromatin pattern, and prominent nucleoli. The cytologic features were correlated with the histologic features in each case of enteric type thymic adenocarcinoma. The differential diagnosis included other thymic carcinomas, yolk sac tumors, and metastatic adenocarcinoma from the lung or colorectum.

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Case report: Primary adenocarcinoma NOS of the thymus and cytological features
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Diagnostic Cytopathology.2023;[Epub] CrossRef
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International Cancer Conference Journal.2022; 12(1): 46. CrossRef
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Medicine.2021; 100(15): e25254. CrossRef
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The Journal of the Japanese Association for Chest Surgery.2020; 34(2): 107. CrossRef
Primary thymic adenocarcinoma with an aggressive clinical course: An autopsy case showing signet ring cell‐like features
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Primary Thymic Signet Ring Cell Adenocarcinoma: A Currently Unrecognized Variant
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International Journal of Surgical Pathology.2019; 27(3): 315. CrossRef
Disseminated and massive tumor burden in a case of primary thymic mucinous adenocarcinoma
Hui-Wen Liu, Chih-Yi Liu, Yi-Chen Yeh
Journal of Cancer Research and Practice.2019; 6(3): 151. CrossRef

Intrahepatic Cholangiocarcinoma with Ductal Plate Malformation-like Feature Associated with Bile Duct Adenoma: Ah-Young Kwon, Hye Jin Lee, Hee Jung An, Haeyoun Kang, Jin-Hyung Heo, Gwangil Kim; J Pathol Transl Med. 2015;49(6):531-534. Published online July 31, 2015; DOI: https://doi.org/10.4132/jptm.2015.06.19

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Histopathological evidence of intrahepatic cholangiocarcinoma occurring in ductal plate malformation: A clinicopathologic study of 5 cases
Qian Wang, Yi Xu, Shou-Mei Wang, Ai-Yan Hu, Yun-Cui Pan, Shu-Hui Zhang
Annals of Diagnostic Pathology.2021; 55: 151828. CrossRef
Cholangiolocellular Carcinoma Arising in a Normal Liver
Chie Kitami, Yasuyuki Kawachi, Toshihiko Igarashi, Shigeto Makino, Atsushi Nishimura, Mikako Kawahara, Keiya Niikuni, Kenichi Harada
The Japanese Journal of Gastroenterological Surgery.2016; 49(10): 1006. CrossRef

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