Fig. 1Radiologic evaluations. (A) Facial bone computed tomography reveals a cyst-like lesion in the right mandibular alveolar process of the first molar. (B) During surgery, the first molar is extracted and a solid, firm mass is found under the molar (arrow).
Fig. 2Microscopic and special staining features. (A) The tumor is highly cellular and exhibits an interlacing fascicle pattern with slit-like blood vessels. Neither atypical mitosis nor necrosis are detected. (B) A high-power view reveals spindle cells with elongated nuclei and blunted-ends closely resembling smooth muscle tumors. (C) Masson's trichrome stain shows plenty of collagenous stroma (blue stain) intermingled with myofibroblastic cells (red stain).
Fig. 3Immunohistochemical stains. (A) Smooth muscle actin is expressed diffusely and strongly in spindle cells. (B) CD34 demonstrates hemangiopericytoma-like vascular pattern. (C) Vimentin is diffusely and strongly positive in all around the tumor cells.
Table 1.Clinicopathologic features of five cases of solitary myofibroma of the adult mandible
Case |
Gender |
Age (yr) |
Treatment |
Oliver et al. [7] |
Female |
34 |
Surgical excision with bone graft |
Sedghizadeh et al. [8] |
Male |
20 |
Surgical excision and reconstruction |
Ramadorai et al. [9] |
Female |
32 |
Surgical excision and reconstruction |
Brierley et al. [6] |
Female |
43 |
Curettage of lesion and extraction of associated mobile teeth |
Our case |
Female |
31 |
Surgical excision and extraction of associated mobile teeth |