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Chang Woo Nam 1 Article
Acute Appendicitis Associated with Aspergillosis in a Leukemia Patient: A Case Report.
Bong Hee Park, Jae Hee Suh, Hye Jeong Choi, Hee Jeong Cha, Chang Woo Nam, Young Min Kim
Korean J Pathol. 2010;44(3):330-332.
DOI: https://doi.org/10.4132/KoreanJPathol.2010.44.3.330
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AbstractAbstract PDF
Herein we describe a rare case of acute appendicitis associated with localized aspergillosis in an 8-year-old boy with acute lymphoblastic leukemia. During chemotherapy, the patient complained of mild abdominal pain in the peri-umbilical area and displayed an increased C-reactive protein level. Abdominal ultrasonography disclosed appendicitis and consequently an appendectomy was done. Histologically, acute appendicitis and Aspergillus hyphae were identified in the lumen and necrotic mucosa. However, there was no evidence of systemic aspergillosis. While aspergillosis is a common fungal infection in immunocompromised patients treated with chemotherapy, acute appendicitis associated with localized aspergillosis without systemic infection is a very rare occurrence.

Citations

Citations to this article as recorded by  
  • A scoping review on acute gastrointestinal surgical complications in immunocompromised pediatric patients
    Tarek Bou Dargham, Mohamad Bahij Moumneh, Christine Atallah, Ahmad Zaghal
    Annals of Pediatric Surgery.2022;[Epub]     CrossRef
  • Acute isolated Aspergillus appendicitis in pediatric leukemia
    Yutaro Yada, Yuhki Koga, Hiroaki Ono, Yoshitomo Motomura, Genshiro Esumi, Kenichi Kohashi, Yasunori Muraosa, Katsuhiko Kamei, Toshiharu Matsuura, Yoshinao Oda, Shouichi Ohga
    Journal of Infection and Chemotherapy.2020; 26(11): 1229.     CrossRef
  • Isolated Acute Appendicitis Caused by Aspergillu s in a Patient Who Underwent Lung Transplantation: A Case Report
    H.S. Kim, H.J. Yeo, D.H. Shin, W.H. Cho, D. Kim
    Transplantation Proceedings.2018; 50(4): 1199.     CrossRef
  • Fungal Appendicitis in Immunocompromised Children. Indications and Contraindications for Laparoscopic Appendectomy: A Report on 2 Successful Cases
    Veronica Carlini, Valeria Calcaterra, Nunzia Decembrino, Laura Rubert, Noemi Pasqua, Mattia Novario, Marco Lucioni, Marco Brunero, Gloria Pelizzo
    Journal of Pediatric Hematology/Oncology.2016; 38(7): 581.     CrossRef
  • Characteristic clinical features ofAspergillusappendicitis: Case report and literature review
    Mihajlo Gjeorgjievski
    World Journal of Gastroenterology.2015; 21(44): 12713.     CrossRef

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