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Epithelioid Angiomyolipoma of the Kidney: A case report.
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HOME > J Pathol Transl Med > Volume 34(11); 2000 > Article
Case Report Epithelioid Angiomyolipoma of the Kidney: A case report.
You Kyung Kim, Jong Sil Lee, Ky Hyun Chung, Sun Hoo Park, Gyung Hyuck Ko
Journal of Pathology and Translational Medicine 2000;34(11):953-956
DOI: https://doi.org/
1Departments of Pathology, Gyeongsang National University College of Medicine, Chinju 660-751, Korea.
2Departments of Urology, Gyeongsang National University College of Medicine, Chinju 660-751, Korea.
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Angiomyolipoma is considered by many authors to be a hamartoma, occurring in a sporadic form or in association with tuberous sclerosis. This lesion consists of thick walled blood vessels, smooth muscle, and mature adipose tissue in varying amounts. We have experienced a case of the angiomyolipoma composed of monotypic epithelioid cells. The patient was a 69-year-old female. Clinically, there was no evidence of tuberous sclerosis. Microscopically, the tumor was composed of polygonal cells with abundant eosinophilic granular or clear cytoplasm, pleomorphic nuclei, prominent nucleoli, and multinucleated giant cells. The tumor cells showed positive reaction for HMB45, CD68, smooth muscle actin, and S-100, and negative reaction for epithelial membrane antigen, cytokeratin, vimentin, desmin, CD34, estrogen receptor, and progesterone receptor. Ultrastructual analysis showed the presence of glycogen, mitochondria, and other microorganelles in neoplastic cells. Melanosome or premelanosome was not identified.


J Pathol Transl Med : Journal of Pathology and Translational Medicine