Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea
1Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
2CHA Bundang Medical Center, CHA University, Seongnam, Korea
3Division of Medical Oncology, Yonsei Cancer Center, Seoul, Korea
4Division of Hematology and Medical Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea
5Division of Oncology, Department of Hematology and Oncology, Ulsan University Hospital, Ulsan, Korea
6Division of Medical Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea
7Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
8Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
© 2018 The Korean Society of Pathologists/The Korean Society for Cytopathology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Conflicts of Interest
No potential conflict of interest relevant to this article was reported.
Sample type | No. of cases compared |
Concordant (NGS/PNA) |
Discordant (NGS/PNA) |
Concordance (%) | |||
---|---|---|---|---|---|---|---|
–/– | +/+ | –/+ | +/– | +/+ | |||
FFPE | 131 | 69 | 53 | 2 | 6 | 1 | 93.1 |
FF | 14 | 5 | 7 | 1 | 1 | 0 | 85.7 |
Total | 145 | 74 | 60 | 3 | 7 | 1 | 92.4 |
Concomitant Mutations in EGFR 19Del/L858R Mutation and Their Association with Response to EGFR-TKIs in NSCLC Patients