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doi: https://doi.org/10.4132/jptm.2017.01.04    [Epub ahead of print]
A Rare Case of Aggressive Melanotic Schwannoma Occurred in Spinal Nerve of a 59-Year-Old Male
Sung-eun Choi1, Yoon Jin Cha1, Jisup Kim1, Hyunseo Cha1, Jayeong Seo1, Sung-Uk Kuh2, Sung-Jun Kim3, Se Hoon Kim4
1Department of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
2Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
3Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
4Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
Corresponding Author: Se Hoon Kim ,Tel: +82-2-2228-1764, Fax: +82-2-362-0860, Email: paxco@yuhs.ac
Received: October 17, 2016;  Revised: December 6, 2016  Accepted: January 4, 2017.  Published online: April 4, 2017.
ABSTRACT
Melanotic schwannoma (MS) is a rare variant of nerve sheath neoplasm that shows ultrastructural and immunophenotypical features of Schwann cells but also has cytoplasmic melanosomes and is reactive for melanocytic markers as well. Unlike conventional schwannoma, which is totally benign, MS has an unpredictable prognosis and is thought to have low-malignant potential. Herein, we present a rare case of recurrent MS in lumbar spine of a 59-year-old male.
Key Words: Melanotic schwannoma; Spine; Recurrence; Metastasis
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