Department of Dental Hygiene, College of Health Sciences, Cheongju University, Cheongju, Korea.
1Department of Oral Pathology, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea.
© 2014 The Korean Society of Pathologists/The Korean Society for Cytopathology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Group | n | Antibody |
---|---|---|
Odontogenic proteins | 3 | Ameloblastina, amelogenina, Krox-2513 |
Growth factor-related proteins | 7 | pAKTb, EGFRc, c-erbB2c, N-RASb, SHHa, SOS-1a, TGF-β1d |
Proliferation-related proteins | 4 | eIF5Ab, NFkBc, p53a, PCNAb |
Apoptosis-related proteins | 4 | BCL-2a, FASa, FASLa, PARPa |
Oncoproteins | 10 | 14-3-3a, CEAb, NF-1c, PIM1d, PTCH1a, STAT3a, survivind, β-cateninec, E-cadherinc, Wnt1a |
Immune proteins | 6 | α1-ATa, CD3a, β-defensin-1a, β-defensin-2a, β-defensin-3a, TNFαa |
Matrix-related proteins | 13 | Cathepsin Gc, cathepsin Kc, CK-7a, EpCama, FAKa, HSP-70a, KL1a, MMP-1b, MMP-2b, MMP-9a, p63a, TGase-1a, TGase-2a |
Angiogenesis-related proteins | 3 | HIFd, VEGFd, vWFb |
Total | 50 |
pAKT1, v-akt murine thymoma viral oncogene homolog 1, phosphorylated at Thr 308; EGFR, epithelial growth factor receptor; SHH, sonic hedgehog; SOS-1, Son of sevenless-1; TGF-β1, transforming growth factor-β1, eIF5A, eukaryotic translation initiation factor 5A; NFkB, nuclear factor kappa-light-chain-enhancer of activated B cells; PCNA, proliferating cell nuclear antigen; BCL-2, B-cell leukemia/lymphoma-2; FASL, FAS (CD95/Apo1) ligand; PARP, poly-ADP ribose polymerase; CEA, carcinoembryonic antigen; NF-1, neurofibromin-1; PIM1, pivotal integration site 1; PTCH1, patched homologue 1; STAT3, signal transducer and activator of transcription-3; α1-AT, α1-antitrypsin; TNFα, tumor nescrosis factor-α; CK, cytokeratin; EpCam, epithelial cell adhesion molecule, Ber-EP4; FAK, focal adhesion kinase; HSP-70, heat shock protein-70; KL1, pan cytokeratin 1, 2, 5, 6, 7, 8, 11, 14, 16, 17, 18; MMP, matrix metalloprotease; TGase, transglutaminase; HIF, hypoxia inducible factor; VEGF, vascular endothelial growth factor; vWF, von Willebrand factor.
a Santa Cruz Biotechnology, Santa Cruz, CA, USA;
b Neomarkers, Fremont, CA, USA;
c DAKO, Glostrup, Denmark;
d Zymed, San Francisco, CA, USA.
PA, peripheral ameloblastoma; OBCC, oral basal cell carcinoma; SOS-1, Son of sevenless-1; EGFR, epithelial growth factor receptor; TGF-β1, transforming growth factor-β1; SHH, sonic hedgehog; pAKT1, v-akt murine thymoma viral oncogene homolog 1, phosphorylated at Thr 308; eIF5A, eukaryotic translation initiation factor 5A; NFkB, nuclear factor kappa-light-chain-enhancer of activated B cells; PCNA, proliferating cell nuclear antigen; BCL-2, B-cell leukemia/lymphoma-2; FASL, FAS (CD95/Apo1) ligand; PARP, poly-ADP ribose polymerase; CEA, carcinoembryonic antigen; PTCH1, patched homologue 1; α1-AT, α1-antitrypsin; NF-1, neurofibromin-1; PIM1, pivotal integration site 1; STAT3, signal transducer and activator of transcription-3; TNFα; tumor nescrosis factor-α; CK-7, cytokeratin 7; HSP-70, heat shock protein-70; MMP, matrix metalloprotease; EpCam, epithelial cell adhesion molecule, Ber-EP4; TGase, transglutaminase; HIF, hypoxia inducible factor; vWF, von Willebrand factor; VEGF, vascular endothelial growth factor.